The success of platinum-based anticancer agents has motivated the exploration of novel
metal-based drugs for several decades, whereas problems such as drug-resistance and …

Hydrogels are a unique class of three dimensional cross-linked polymeric networks that can
hold a large fraction of aqueous solvents and biological fluids within their structures …

Micelles have been studied as drug delivery carriers for decades. Their use can potentially
result in high drug accumulation at the target site through the enhanced permeability and …

Nanogels have emerged as a versatile hydrophilic platform for encapsulation of guest
molecules with a capability to respond to external stimuli that can be used for a multitude of …

Due to their high specific surface area, graphene oxide and graphene oxide-base
nanoparticles have great potential both in dual-drug delivery and combination …

Abstract pH-responsive polymers contain ionic functional groups as pendants in their
structure. The total number of charged groups on polymer chains determines the overall …

Platinum based anticancer drugs have revolutionized cancer chemotherapy, and continue to
be in widespread clinical use especially for management of tumors of the ovary, testes, and …

Titratable polyanions, and more particularly polymers bearing carboxylate groups, have
been used in recent years to produce a variety of pH-sensitive colloids. These polymers …

Platinum drugs comprise of almost 50% of all currently used anticancer drugs. They are now
widely used in the clinical therapy of various solid tumors, including ovarian, head and neck …

The use of biodegradable polymeric nanoparticles (NPs) for controlled drug delivery has
shown significant therapeutic potential. Concurrently, targeted delivery technologies are …