[HTML][HTML] Transcriptome comparison of meniscus from patients with and without osteoarthritis

RH Brophy, B Zhang, L Cai, RW Wright… - Osteoarthritis and …, 2018 - Elsevier
Objective To assess the impact of osteoarthritis (OA) on the meniscus by comparing
transcripts and biological processes in the meniscus between patients with and without OA …

What did we learn from 'omics' studies in osteoarthritis

C Ruiz-Romero, I Rego-Perez… - Current Opinion in …, 2018 - journals.lww.com
This review describes the most recent 'omics' studies in OA research, their conclusions, and
discuss those remaining challenges. Still many validation studies must be performed in …

Comprehensive analysis of key genes, signaling pathways and miRNAs in human knee osteoarthritis: based on bioinformatics

L Chang, H Yao, Z Yao, KKW Ho, MTY Ong… - Frontiers in …, 2021 - frontiersin.org
Background: Osteoarthritis (OA) is one of the main causes of disability in the elderly
population, accompanied by a series of underlying pathologic changes, such as cartilage …

Gene expression in glenoid articular cartilage varies across acute instability, chronic instability, and osteoarthritis

AW Aleem, MF Rai, L Cai, RH Brophy - JBJS, 2023 - journals.lww.com
Background: Shoulder instability is a common pathology associated with an elevated risk of
osteoarthritis (OA). Little is known about gene expression in the cartilage of the …

Gene expression profiles of peripheral blood monocytes in osteoarthritis and analysis of differentially expressed genes

T Shi, X Shen, G Gao - BioMed Research International, 2019 - Wiley Online Library
Background. There is little understanding of the molecular processes involved in the
pathogenesis of osteoarthritis, limiting early diagnosis and effective treatment of OA. Use of …

[HTML][HTML] Distinct degenerative phenotype of articular cartilage from knees with meniscus tear compared to knees with osteoarthritis

MF Rai, ED Tycksen, L Cai, J Yu, RW Wright… - Osteoarthritis and …, 2019 - Elsevier
Objective To compare the transcriptome of articular cartilage from knees with meniscus tears
to knees with end-stage osteoarthritis (OA). Design Articular cartilage was collected from the …

MicroRNA-1202 plays a vital role in osteoarthritis via KCNQ1OT1 has-miR-1202-ETS1 regulatory pathway

C Liu, J Gao, G Su, Y Xiang, L Wan - Journal of orthopaedic surgery and …, 2020 - Springer
Background This study aimed to explore the molecular mechanism of osteoarthritis (OA) and
provide information about new genes as potential targets for OA treatment. Methods Gene …

Combined bioinformatics analysis reveals gene expression and DNA methylation patterns in osteoarthritis

D Song, W Qi, M Lv, C Yuan… - Molecular Medicine …, 2018 - spandidos-publications.com
Osteoarthritis (OA) is a common type of arthritis, which may cause pain and disability.
Alterations in gene expression and DNA methylation have been proven to be associated …

Label-free quantitative proteomics positions the effects and mechanisms of Herba Lysimachiae on synovial diseases based on biolabel-led research pattern

XZ Li, HJ Huang, SN Zhang, Q Liu, YM Wang - Journal of Chromatography …, 2020 - Elsevier
Some previous studies have demonstrated that Herba Lysimachiae (HL) has a certain
protective effect on synovial lesion. But the synovial diseases HL is suitable for treating have …

Cell-integrated serum-induced signalling patterns can differentiate between hand and knee osteoarthritis patients

M Neefjes, BAC Housmans, C Kaffa… - …, 2024 - academic.oup.com
Objective OA is a very heterogeneous disease. Here, we aimed to differentiate OA patients
based on their serum-induced cell-integrated signalling patterns. Design In order to monitor …