Molecular mimicry of the viral spike in the SARS-CoV-2 vaccine possibly triggers transient dysregulation of ACE2, leading to vascular and coagulation dysfunction …

CA Devaux, L Camoin-Jau - Viruses, 2023 - mdpi.com
The benefits of SARS-CoV-2 spike mRNA vaccines are well known, including a significant
decline in COVID-19 morbidity and a decrease in the mortality rate of SARS-CoV-2 infected …

Unravelling antigenic cross-reactions toward the world of coronaviruses: extent of the stability of shared epitopes and SARS-CoV-2 anti-spike cross-neutralizing …

CA Devaux, J Fantini - Pathogens, 2023 - mdpi.com
The human immune repertoire retains the molecular memory of a very great diversity of
target antigens (epitopes) and can recall this upon a second encounter with epitopes …

Pre-existing cross-reactive neutralizing activity against SARS-CoV-2 and seasonal coronaviruses prior to the COVID-19 pandemic (2014-2019) with limited immunity …

TTN Nguyen, EM Choo, Y Nakamura, R Suzuki… - International Journal of …, 2024 - Elsevier
Objectives SARS-CoV-2 transmission and epidemic potential is related to the population's
immunity levels. As such, assessing different regions' preexisting immune responses to …

Predicting Vaccine Effectiveness for Hospitalization and Symptomatic Disease for Novel SARS-CoV-2 Variants Using Neutralizing Antibody Titers

BJ Gardner, AM Kilpatrick - Viruses, 2024 - mdpi.com
The emergence of new virus variants, including the Omicron variant (B. 1.1. 529) of SARS-
CoV-2, can lead to reduced vaccine effectiveness (VE) and the need for new vaccines or …

Alternative splicing expands the antiviral IFITM repertoire in Chinese rufous horseshoe bats

NSC Mak, J Liu, D Zhang, J Taylor, X Li… - PLoS …, 2024 - journals.plos.org
Species-specific interferon responses are shaped by the virus-host arms race. The human
interferon-induced transmembrane protein (IFITM) family consists of three antiviral IFITM …

[HTML][HTML] Construction of pseudotyped human coronaviruses and detection of pre-existing antibodies in the human population

Q Jiang, X Wu, F Dong, S Qiao, Q Shi, C Jian… - Biosafety and …, 2024 - Elsevier
In order to clarify the pre-exist immunity background of different human coronaviruses
(HCoV), this study investigated the positive rate of spike (S) protein antibodies of HCoV …

Studying Host-Virus Interactions with Pseudotyped Viruses (Video)| JoVE

T Fantoni, M Bissoli, C Stefani, M Voi, A Dabija… - JoVE (Journal of …, 2023 - jove.com
Pseudotyped viruses (PVs) are molecular tools that can be used to study host-virus
interactions and to test the neutralizing ability of serum samples, in addition to their better …

Circulating Synthetic SARS-CoV-2 Spike Proteins Possibly Contribute to a Transient ACE2 Dysfunction Leading to Rare Cases of Myocarditis after COVID-19 mRNA …

CA Devaux, P Colson, D Raoult, L Camoin-Jau - 2023 - preprints.org
Myocarditis has been recognized as a possible rare complication of COVID-19 mRNA
vaccination. It concerns between one and five vaccinated people per 100,000 in the general …

The use of SARS-CoV-2 pseudoviruses to investigate the neutralizing immunity and the pathogenesis of COVID-19

T Fantoni - 2024 - iris.univr.it
Abstract The Coronavirus Disease–19 (COVID-19) occurs following SARS-CoV-2 infection
with a wide spectrum of symptoms, which degenerate into severe acute respiratory …