Background and Purpose: Population-wide reductions in cardiovascular disease incidence
and mortality have not been shared equally by African Americans. The burden of …

Cardiovascular disease (CVD) accounts for a third of all deaths in the United States making
it the leading cause of morbidity and mortality. Although CVD affects individuals of all …

Blacks have the highest prevalence of hypertension, putting them at greater risk of
cardiovascular disease and death. Previous studies have reported that, relative to whites …

Objectives—Controversy exists over the effect of acute hyperglycemia on vascular function.
In this systematic review, we compared the effect of acute hyperglycemia on endothelial and …

The endothelium controls vascular tone not only by releasing various vasoactive substances
but also by another pathway associated with the hyperpolarization of both endothelial and …

Heart failure (HF) remains a condition associated with high morbidity, mortality, and
associated costs. Although the number of medical and device-based therapies available to …

This approach might be extremely useful to investigate in vivo endothelial function in murine
models of vascular diseases and in genetically modified mice. In humans, endothelium …

Physical inactivity is a major risk factor for the development of obesity and other
cardiovascular (CV) disease (CVD). Vascular endothelial dysfunction is a key event in the …

Endothelium, acting as a barrier, protects tissues against factors that provoke insulin
resistance and type 2 diabetes and itself responds to the insult of insulin resistance inducers …

The black population exhibits attenuated vasodilatory function across their lifespan, yet little
is known regarding the mechanisms of this impairment. Recent evidence suggests a …