Development of the human placenta and fetal heart: synergic or independent?

GJ Burton, E Jauniaux - Frontiers in physiology, 2018 - frontiersin.org
The placenta is the largest fetal organ, and toward the end of pregnancy the umbilical
circulation receives at least 40% of the biventricular cardiac output. It is not surprising …

[HTML][HTML] Placenta morphology and biomarkers in pregnancies with congenital heart disease–a systematic review

MC Snoep, M Aliasi, LE van der Meeren… - Placenta, 2021 - Elsevier
Impaired placentation is an important contributing factor to intra-uterine growth restriction
and pre-eclampsia in fetuses with congenital heart defects (CHD). These pregnancy …

Characterization of the placenta in the newborn with congenital heart disease: distinctions based on type of cardiac malformation

J Rychik, D Goff, E McKay, A Mott, Z Tian, DJ Licht… - Pediatric …, 2018 - Springer
The placenta is a complex organ that influences prenatal growth and development, and
through fetal programming impacts postnatal health and well-being lifelong. Little …

Non-invasive placental perfusion imaging in pregnancies complicated by fetal heart disease using velocity-selective arterial spin labeled MRI

Z Zun, G Zaharchuk, NN Andescavage, MT Donofrio… - Scientific reports, 2017 - nature.com
The placenta is a vital organ for fetal growth and development during pregnancy. Congenital
heart disease (CHD) is a leading cause of morbidity and mortality in newborns. Despite the …

Angiogenic factors and long-term cardiovascular risk in women that developed preeclampsia during pregnancy

C Garrido-Gimenez, M Mendoza, M Cruz-Lemini… - …, 2020 - Am Heart Assoc
Preeclampsia is caused by placental impairment with increased expression of sFlt-1
(soluble fms-like tyrosine kinase 1) and decreased PlGF (placental growth factor); it has …

Longitudinal changes in fetal biometry and cerebroplacental hemodynamics in fetuses with congenital heart disease

A Ruiz, M Cruz‐Lemini, N Masoller… - … in Obstetrics & …, 2017 - Wiley Online Library
Objectives To determine the longitudinal behavior of fetal biometric measures and
cerebroplacental hemodynamics throughout gestation in fetuses with congenital heart …

Shared developmental pathways of the placenta and fetal heart

A Mahadevan, A Tipler, H Jones - Placenta, 2023 - Elsevier
Congenital heart defects (CHD) remain the most common class of birth defect worldwide,
affecting 1 in every 110 live births. A host of clinical and morphological indicators of …

[HTML][HTML] Placental abnormalities in congenital heart disease

NN Andescavage, C Limperopoulos - Translational pediatrics, 2021 - ncbi.nlm.nih.gov
Congenital heart disease (CHD) remains the most common birth defect in infants, and
critical CHD is associated with significant rates of morbidity and mortality. With the advent of …

Placental pathology and neuroimaging correlates in neonates with congenital heart disease

SD Schlatterer, J Murnick, M Jacobs, L White… - Scientific reports, 2019 - nature.com
Congenital heart disease (CHD) is an independent risk factor for brain injury, including
stroke, and poor neurodevelopmental outcomes, and placental abnormalities may represent …

The impact of the maternal–foetal environment on outcomes of surgery for congenital heart disease in neonates

JW Gaynor, S Parry, JS Moldenhauer… - European Journal of …, 2018 - academic.oup.com
OBJECTIVES Pregnancies with congenital heart disease in the foetus have an increased
prevalence of pre-eclampsia, small for gestational age and preterm birth, which are …