Host–Pathogen interactions influencing zoonotic spillover potential and transmission in humans
Emerging infectious diseases of zoonotic origin are an ever-increasing public health risk
and economic burden. The factors that determine if and when an animal virus is able to spill …
and economic burden. The factors that determine if and when an animal virus is able to spill …
14‐3‐3 Family of Proteins: Biological Implications, Molecular Interactions, and Potential Intervention in Cancer, Virus and Neurodegeneration Disorders
ABSTRACT The 14‐3‐3 family of proteins are highly conserved acidic eukaryotic proteins
(25–32 kDa) abundantly present in the body. Through numerous binding partners, the 14‐3 …
(25–32 kDa) abundantly present in the body. Through numerous binding partners, the 14‐3 …
Functional benefit of structural disorder for the replication of measles, Nipah and Hendra viruses
F Gondelaud, G Pesce, JF Nilsson… - Essays in …, 2022 - portlandpress.com
Abstract Measles, Nipah and Hendra viruses are severe human pathogens within the
Paramyxoviridae family. Their non-segmented, single-stranded, negative-sense RNA …
Paramyxoviridae family. Their non-segmented, single-stranded, negative-sense RNA …
Fruit bats as natural reservoir of highly pathogenic henipaviruses: balance between antiviral defense and viral tolerance
Highlights•Bats are asymptomatic reservoir of numerous deadly viruses including
Henipavirus.•Bats could dampen inflammation following positive selection of many immune …
Henipavirus.•Bats could dampen inflammation following positive selection of many immune …
Structural basis for SARS-CoV-2 nucleocapsid (N) protein recognition by 14-3-3 proteins
A Eisenreichova, E Boura - Journal of Structural Biology, 2022 - Elsevier
3-3 proteins are important dimeric scaffolds that regulate the function of hundreds of proteins
in a phosphorylation-dependent manner. The SARS-CoV-2 nucleocapsid (N) protein forms …
in a phosphorylation-dependent manner. The SARS-CoV-2 nucleocapsid (N) protein forms …
Sinomenine attenuated dextran sulfate sodium-induced inflammatory responses by promoting 14-3-3θ protein and inhibiting NF-κB signaling
Y Zhou, S Chen, Y Dai, L Wu, M Jin, J Zhao, Y Li… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance The rhizome of Chinese medical plant QingTeng (scientific
name: Sinomenium acutum (Thunb.) Rehd. et Wils.) is widely used by traditional medical …
name: Sinomenium acutum (Thunb.) Rehd. et Wils.) is widely used by traditional medical …
Dissecting Henipavirus W proteins conformational and fibrillation properties: contribution of their N‐ and C‐terminal constituent domains
G Pesce, F Gondelaud, D Ptchelkine… - The FEBS …, 2024 - Wiley Online Library
The Nipah and Hendra viruses are severe human pathogens. In addition to the P protein,
their P gene also encodes the V and W proteins that share with P their N‐terminal …
their P gene also encodes the V and W proteins that share with P their N‐terminal …
Qualitative analysis of Fasciola gigantica excretory and secretory products coimmunoprecipitated with buffalo secondary infection sera shows dissimilar components …
M Zheng, X Kong, X Jiang, Y Yang, S Fu, C Wen… - Acta Tropica, 2024 - Elsevier
Buffaloes cannot mount a robust adaptive immune response to secondary infection by
Fasciola gigantica. Even if excretory and secretory products (ESPs) exhibit potent …
Fasciola gigantica. Even if excretory and secretory products (ESPs) exhibit potent …
Amentoflavone maintaining extracellular matrix homeostasis and inhibiting subchondral bone loss in osteoarthritis by inhibiting ERK, JNK and NF-κB signaling …
J Liang, J Hu, X Hong, M Zhou, G Xia, L Hu… - Journal of Orthopaedic …, 2024 - Springer
Amentoflavone (AF), a plant biflavone isolated from Selaginella sinensis ethanol extract, is
characterized by anti-inflammatory and anti-oxidant properties. According to previous …
characterized by anti-inflammatory and anti-oxidant properties. According to previous …
YWHAG inhibits influenza a virus replication by suppressing the release of viral M2 protein
H Mao, L Cao, T Xu, X Xia, P Ren, P Han, C Li… - Frontiers in …, 2022 - frontiersin.org
Influenza A virus (IAV) poses a serious threat to human life and property. The IAV matrix
protein 2 (M2) is significant in viral budding. Increasing studies have proven the important …
protein 2 (M2) is significant in viral budding. Increasing studies have proven the important …