Next-generation sequencing: insights to advance clinical investigations of the microbiome

CR Wensel, JL Pluznick, SL Salzberg… - The Journal of clinical …, 2022 - Am Soc Clin Investig
Next-generation sequencing (NGS) technology has advanced our understanding of the
human microbiome by allowing for the discovery and characterization of unculturable …

Periodontitis and implant complications in diabetes

L Nibali, N Gkranias, G Mainas… - Periodontology 2000, 2022 - Wiley Online Library
Epidemiologic evidence indicates that periodontitis is more frequent in patients with
uncontrolled diabetes mellitus than in healthy controls, suggesting that it could be …

Association between metabolic syndrome and periodontitis: The role of lipids, inflammatory cytokines, altered host response, and the microbiome

FQ Pirih, S Monajemzadeh, N Singh… - Periodontology …, 2021 - Wiley Online Library
Periodontitis has been associated with many systemic diseases and conditions, including
metabolic syndrome. Metabolic syndrome is a cluster of conditions that occur concomitantly …

The impact of diabetes on periodontal diseases

DT Graves, Z Ding, Y Yang - Periodontology 2000, 2020 - Wiley Online Library
The susceptibility and severity of periodontal diseases is made more severe by diabetes,
with the impact on the disease process inversely proportional to the level of glycemic control …

The oral microbiota is modified by systemic diseases

DT Graves, JD Corrêa, TA Silva - Journal of dental research, 2019 - journals.sagepub.com
Periodontal diseases are initiated by bacteria that accumulate in a biofilm on the tooth
surface and affect the adjacent periodontal tissue. Systemic diseases such as diabetes …

An update on the evidence for pathogenic mechanisms that may link periodontitis and diabetes

D Polak, L Shapira - Journal of clinical periodontology, 2018 - Wiley Online Library
Aim To provide an update of the review by Taylor (Journal of Clinical Periodontology, 2013,
40, S113) regarding the scientific evidence of the biological association between …

From focal sepsis to periodontal medicine: a century of exploring the role of the oral microbiome in systemic disease

PS Kumar - The Journal of physiology, 2017 - Wiley Online Library
The oral microbiome is established within a few minutes after birth and consists of stable
multi‐species communities that engage in a dynamic equilibrium with the host immune …

Comparing apples and oranges?: next generation sequencing and its impact on microbiome analysis

AG Clooney, F Fouhy, RD Sleator, A O'Driscoll… - PloS one, 2016 - journals.plos.org
Rapid advancements in sequencing technologies along with falling costs present
widespread opportunities for microbiome studies across a vast and diverse array of …

Impact of systemic factors in shaping the periodontal microbiome

F Teles, Y Wang, G Hajishengallis… - Periodontology …, 2021 - Wiley Online Library
Since 2010, next‐generation sequencing platforms have laid the foundation to an exciting
phase of discovery in oral microbiology as it relates to oral and systemic health and disease …

Dysbiosis of salivary microbiome and cytokines influence oral squamous cell carcinoma through inflammation

AK Rai, M Panda, AK Das, T Rahman, R Das… - Archives of …, 2021 - Springer
Advanced combinatorial treatments of surgery, chemotherapy, and radiotherapy do not have
any effect on the enhancement of a 5-year survival rate of oral squamous cell carcinoma …