The S100B story: from biomarker to active factor in neural injury

F Michetti, N D'Ambrosi, A Toesca… - Journal of …, 2019 - Wiley Online Library
S100B is a Ca2+‐binding protein mainly concentrated in astrocytes. Its levels in biological
fluids (cerebrospinal fluid, peripheral and cord blood, urine, saliva, amniotic fluid) are …

Biological aspects of selected myokines in skeletal muscle: focus on aging

R Mancinelli, F Checcaglini, F Coscia… - International journal of …, 2021 - mdpi.com
In the last decade, clear evidence has emerged that the cellular components of skeletal
muscle are important sites for the release of proteins and peptides called “myokines” …

The S100 family of EF-hand calcium-binding proteins: functions and pathology

BW Schäfer, CW Heizmann - Trends in biochemical sciences, 1996 - cell.com
Calcium ions as second messengers control many biological processes, at least in part, via
interaction with a large number of Ca 2+-binding proteins. One class of these proteins …

[HTML][HTML] Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type

R Donato - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 1999 - Elsevier
A multigenic family of Ca2+-binding proteins of the EF-hand type known as S100 comprises
19 members that are differentially expressed in a large number of cell types. Members of this …

Calcium-dependent and-independent interactions of the S100 protein family

L Santamaria-Kisiel, AC Rintala-Dempsey… - Biochemical …, 2006 - portlandpress.com
The S100 proteins comprise at least 25 members, forming the largest group of EF-hand
signalling proteins in humans. Although the proteins are expressed in many tissues, each …

S-100 protein and neuron-specific enolase concentrations in blood as indicators of infarction volume and prognosis in acute ischemic stroke

U Missler, M Wiesmann, C Friedrich, M Kaps - Stroke, 1997 - Am Heart Assoc
Background and Purpose Better techniques are needed to monitor infarction volume and
predict neurological outcome after ischemic brain infarction. We evaluated the usefulness of …

Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis

H Tanjore, XC Xu, VV Polosukhin… - American journal of …, 2009 - atsjournals.org
Rationale: Lung fibroblasts are key mediators of fibrosis resulting in accumulation of
excessive interstitial collagen and extracellular matrix, but their origins are not well defined …

The S100B protein in biological fluids: more than a lifelong biomarker of brain distress

F Michetti, V Corvino, MC Geloso… - Journal of …, 2012 - Wiley Online Library
J. Neurochem.(2012) 120, 644–659. Abstract S100B is a calcium‐binding protein
concentrated in glial cells, although it has also been detected in definite extra‐neural cell …

Release of glial tissue–specific proteins after acute stroke: a comparative analysis of serum concentrations of protein S-100B and glial fibrillary acidic protein

M Herrmann, P Vos, MT Wunderlich, CHMM de Bruijn… - Stroke, 2000 - Am Heart Assoc
Background and Purpose—This study was aimed at the comparative analysis of serum
concentrations of glial fibrillary acidic protein (GFAP) and protein S-100B in patients with …

Early role of Fsp1 in epithelial-mesenchymal transformation

H Okada, TM Danoff, R Kalluri… - American Journal of …, 1997 - journals.physiology.org
A seamless plasticity exists among cells shifting between epithelial and mesenchymal
phenotypes during early development and again later, in adult tissues, following wound …