DNA methylation and regulation of gene expression: Guardian of our health

GA Dhar, S Saha, P Mitra, R Nag Chaudhuri - The Nucleus, 2021 - Springer
One of the most critical epigenetic signatures present in the genome of higher eukaryotes is
the methylation of DNA at the C-5 position of the cytosine ring. Based on the sites of DNA …

Adult stem cells at work: regenerating skeletal muscle

M Schmidt, SC Schüler, SS Hüttner, B von Eyss… - Cellular and Molecular …, 2019 - Springer
Skeletal muscle regeneration is a finely tuned process involving the activation of various
cellular and molecular processes. Satellite cells, the stem cells of skeletal muscle, are …

Functional non-coding RNA during embryonic myogenesis and postnatal muscle development and disease

H Luo, W Lv, Q Tong, J Jin, Z Xu, B Zuo - Frontiers in cell and …, 2021 - frontiersin.org
Skeletal muscle is a highly heterogeneous tissue that plays a crucial role in mammalian
metabolism and motion maintenance. Myogenesis is a complex biological process that …

MicroRNAs in skeletal muscle and hints on their potential role in muscle wasting during cancer cachexia

GP Marceca, G Nigita, F Calore, CM Croce - Frontiers in oncology, 2020 - frontiersin.org
Cancer-associated cachexia is a heterogeneous, multifactorial syndrome characterized by
systemic inflammation, unintentional weight loss, and profound alteration in body …

Analyses of MicroRNA and mRNA expression profiles reveal the crucial interaction networks and pathways for regulation of chicken breast muscle development

Y Li, Y Chen, W Jin, S Fu, D Li, Y Zhang, G Sun… - Frontiers in …, 2019 - frontiersin.org
There is a lack of understanding surrounding the molecular mechanisms involved in the
development of chicken skeletal muscle in the late postnatal stage, especially in the …

Modulation and evolution of animal development through microRNA regulation of gene expression

S Kittelmann, AP McGregor - Genes, 2019 - mdpi.com
microRNAs regulate gene expression by blocking the translation of mRNAs and/or
promoting their degradation. They, therefore, play important roles in gene regulatory …

Long noncoding RNA DIO3OS hinders cell malignant behaviors of hepatocellular carcinoma cells through the microRNA-328/Hhip Axis

Z Wang, L Song, Y Ye, W Li - Cancer management and research, 2020 - Taylor & Francis
Background The decline of a long non-coding RNA (lncRNA) DIO3OS was implicated in a
plethora of cancers, while the relevance in hepatocellular carcinoma (HCC) has not been …

Somite development and regionalisation of the vertebral axial skeleton

SA Weldon, AE Münsterberg - Seminars in Cell & Developmental Biology, 2022 - Elsevier
A critical stage in the development of all vertebrate embryos is the generation of the body
plan and its subsequent patterning and regionalisation along the main anterior-posterior …

Micro (RNA)-managing muscle wasting

AJ Sannicandro, A Soriano-Arroquia… - Journal of Applied …, 2019 - journals.physiology.org
Progressive skeletal muscle wasting is a natural consequence of aging and is common in
chronic and acute diseases. Loss of skeletal muscle mass and function (strength) often …

MicroRNA-24-3p promotes skeletal muscle differentiation and regeneration by regulating HMGA1

P Dey, MA Soyer, BK Dey - Cellular and Molecular Life Sciences, 2022 - Springer
Numerous studies have established the critical roles of microRNAs in regulating post-
transcriptional gene expression in diverse biological processes. Here, we report on the role …