Nitric oxide (NO) is a gaseous biomolecule endogenously synthesized with an essential role
in embryonic development and several physiological functions, such as regulating …

Acute myeloid leukemia (AML) is a hematologic malignancy caused by a wide range of
alterations responsible for a high grade of heterogeneity among patients. Several studies …

Systemic infections, especially in patients with chronic diseases, may result in sepsis: an
explosive, uncoordinated immune response that can lead to multisystem organ failure with a …

Nutritional interventions are a promising therapeutic option for addressing obesity and
cardiometabolic dysfunction. One such option, intermittent fasting (IF), has emerged as a …

Background Pregnant women and their fetuses are particularly susceptible to respiratory
pathogens. How they respond to SARS-CoV-2 infection is still under investigation. Methods …

The gut microbiome (GM) modulates body weight/composition and gastrointestinal
functioning; therefore, approaches targeting resident gut microbes have attracted …

Erythropoiesis, the development of erythrocytes from hematopoietic stem cells, occurs
through four phases: erythroid progenitor (EP) development, early erythropoiesis, terminal …

Severe COVID-19 alters the biochemical and morphological characteristics of blood cells in
a wide variety of ways. To date, however, the vast majority of research has been devoted to …

To cope with hypoxic stress, ancient organisms have developed evolutionally conserved
programs centered on hypoxia-inducible transcriptional factors (HIFs). HIFs and their …

Transfusion of donor‐derived red blood cells (RBCs) is the most common form of cell
therapy. Production of transfusion‐ready cultured RBCs (cRBCs) is a promising replacement …