The genetically encoded fluorescent sensors convert chemical and physical signals into
light. They are powerful tools for the visualisation of physiological processes in living cells …

Developmental patterning is essential for regulating cellular events such as axial patterning,
segmentation, tissue formation, and organ size determination during embryogenesis …

Potassium ion (K+) is the most abundant metal ion in cells and plays an indispensable role
in practically all biological systems. Although there have been reports of both synthetic and …

Metal ions intersect a wide range of biological processes. Some metal ions are essential
and hence absolutely required for the growth and health of an organism, others are toxic …

Understanding mechanisms of nutrient allocation in organisms requires precise knowledge
of the spatiotemporal dynamics of small molecules in vivo. Genetically encoded sensors are …

Cellular function is controlled through intricate networks of signals, which lead to the myriad
pathways governing cell fate. Fluorescent biosensors have enabled the study of these …

Unpredictable natural disasters, disease outbreaks, climate change, pollution, and war
constantly threaten food crop production. Smart and precision farming encourages using …

A grand challenge in biosensor design is to develop a single-molecule, fluorescent protein-
based platform that can be easily adapted to recognize targets of choice. Here, we created a …

Neuronal activity is accompanied by a net outflow of potassium ions (K+) from the intra-to the
extracellular space. While extracellular [K+] changes during neuronal activity are well …

During neuronal activity, the extracellular concentration of potassium ions ([K+] o) increases
substantially above resting levels, yet it remains unclear what role these [K+] o changes play …