Nanotechnology-based ocular drug delivery systems: recent advances and future prospects

S Li, L Chen, Y Fu - Journal of Nanobiotechnology, 2023 - Springer
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

Developments in Emerging Topical Drug Delivery Systems for Ocular Disorders

S Mandal, P Vishvakarma… - Current Drug Research …, 2024 - benthamdirect.com
According to the current information, using nano gels in the eyes have therapeutic benefits.
Industry growth in the pharmaceutical and healthcare sectors has been filled by …

A recent overview of surfactant–drug interactions and their importance

DR Pokhrel, MK Sah, B Gautam, HK Basak… - RSC …, 2023 - pubs.rsc.org
This review focuses on the self-aggregation properties of different drugs, as well as on their
interaction with anionic, cationic, and gemini surfactants. The interaction of drugs with …

An insight on ophthalmic drug delivery systems: focus on polymeric biomaterials-based carriers

M Shafiq, M Rafique, Y Cui, L Pan, CW Do… - Journal of Controlled …, 2023 - Elsevier
Presently, different types of eye diseases, such as glaucoma, myopia, infection, and dry eyes
are treated with topical eye drops. However, due to ocular surface barriers, eye drops …

[HTML][HTML] Electrospun nanofibers: Exploring process parameters, polymer selection, and recent applications in pharmaceuticals and drug delivery

R Abdulhussain, A Adebisi, BR Conway… - Journal of Drug Delivery …, 2023 - Elsevier
Electrospinning is acknowledged as a versatile technique for producing polymer nanofibers.
Various methods, such as template synthesis, self-assembly, phase separation, and …

[HTML][HTML] Up-to-date molecular medicine strategies for management of ocular surface neovascularization

Y Yang, J Zhong, D Cui, LD Jensen - Advanced Drug Delivery Reviews, 2023 - Elsevier
Ocular surface neovascularization and its resulting pathological changes significantly alter
corneal refraction and obstruct light path to the retina, and hence is a major cause of vision …

[HTML][HTML] Extracellular vesicles in degenerative retinal diseases: A new therapeutic paradigm

F Manai, A Smedowski, K Kaarniranta… - Journal of Controlled …, 2024 - Elsevier
Nanoscale extracellular vesicles (EVs), consisting of exomers, exosomes and microvesicles/
ectosomes, have been extensively investigated in the last 20 years, although their biological …

Transdermal application of diacerin loaded-terpene enriched invasomes: an approach to augment anti-edema and nociception inhibition activity

S Ahmed, MM Farag, MA Sadek… - Journal of Liposome …, 2024 - Taylor & Francis
This study aimed to formulate diacerein loaded terpene-enriched invasomes (DCN-TINV) to
fulfill a fruitful management of osteoarthritis. A 23 factorial design was adopted, including A …

Absorption enhancement strategies in chitosan-based nanosystems and hydrogels intended for ocular delivery: Latest advances for optimization of drug permeation

I Dmour - Carbohydrate Polymers, 2024 - Elsevier
Ophthalmic diseases can be presented as acute diseases like allergies, ocular infections,
etc., or chronic ones that can be manifested as a result of systemic disorders, like diabetes …

Multifunctional cerium oxide nanozyme for synergistic dry eye disease therapy

H Zou, Y Hong, B Xu, M Wang, H Xie… - ACS Applied Materials …, 2024 - ACS Publications
Dry eye disease (DED) is a chronic multifactorial ocular surface disease mainly caused by
the instability of tear film, characterized by a series of ocular discomforts and even visual …