The role of thiols in antioxidant systems

K Ulrich, U Jakob - Free Radical Biology and Medicine, 2019 - Elsevier
The sulfur biochemistry of the thiol group endows cysteines with a number of highly
specialized and unique features that enable them to serve a variety of different functions in …

In vivo imaging with genetically encoded redox biosensors

AI Kostyuk, AS Panova, AD Kokova, DA Kotova… - International journal of …, 2020 - mdpi.com
Redox reactions are of high fundamental and practical interest since they are involved in
both normal physiology and the pathogenesis of various diseases. However, this area of …

Lysozyme-based nanozyme encapsulated in double-network hydrogel for monitoring and repair of MRSA infected wounds

G Le, Y Li, L Cai, L Zhang, W Pei, X Zhu, S Xu… - Chemical Engineering …, 2023 - Elsevier
The presence of bacterial infection at the wound site poses a huge socioeconomic burden to
public health as it adversely affects the tissue regeneration and thereby prolongs the wound …

Salmonella Typhimurium outer membrane protein A (OmpA) renders protection from nitrosative stress of macrophages by maintaining the stability of bacterial outer …

A Roy Chowdhury, S Sah, U Varshney… - PLoS …, 2022 - journals.plos.org
Bacterial porins are highly conserved outer membrane proteins used in the selective
transport of charged molecules across the membrane. In addition to their significant …

Digital models in biotechnology: towards multi-scale integration and implementation

FSF Hartmann, IA Udugama, GM Seibold… - Biotechnology …, 2022 - Elsevier
Industrial biotechnology encompasses a large area of multi-scale and multi-disciplinary
research activities. With the recent megatrend of digitalization sweeping across all …

Molecular mechanisms of glutaredoxin enzymes: versatile hubs for thiol–disulfide exchange between protein thiols and glutathione

Z Xiao, S La Fontaine, AI Bush, AG Wedd - Journal of molecular biology, 2019 - Elsevier
The tripeptide glutathione (GSH) and its oxidized form glutathione disulfide (GSSG)
constitute a key redox couple in cells. In particular, they partner protein thiols in reversible …

[HTML][HTML] Salmonella Typhimurium outer membrane protein A (OmpA) renders protection from nitrosative stress of macrophages by maintaining the stability of bacterial …

AR Chowdhury, S Sah, U Varshney… - PLoS …, 2022 - ncbi.nlm.nih.gov
Bacterial porins are highly conserved outer membrane proteins used in the selective
transport of charged molecules across the membrane. In addition to their significant …

Staphylococcus aureus Uses the Bacilliredoxin (BrxAB)/Bacillithiol Disulfide Reductase (YpdA) Redox Pathway to Defend Against Oxidative Stress Under Infections

N Linzner, VV Loi, VN Fritsch, QN Tung… - Frontiers in …, 2019 - frontiersin.org
Staphylococcus aureus is a major human pathogen and has to cope with reactive oxygen
and chlorine species (ROS, RCS) during infections. The low molecular weight thiol …

Redox regulation in host-pathogen interactions: thiol switches and beyond

M Varatnitskaya, A Degrossoli, LI Leichert - Biological Chemistry, 2021 - degruyter.com
Our organism is exposed to pathogens on a daily basis. Owing to this age-old interaction,
both pathogen and host evolved strategies to cope with these encounters. Here, we focus on …

The AGXX® Antimicrobial Coating Causes a Thiol-Specific Oxidative Stress Response and Protein S-bacillithiolation in Staphylococcus aureus

VV Loi, T Busche, T Preuß, J Kalinowski… - Frontiers in …, 2018 - frontiersin.org
Multidrug-resistant pathogens, such as methicillin-resistant Staphylococcus aureus (MRSA)
pose an increasing health burden and demand alternative antimicrobials to treat bacterial …