[HTML][HTML] Emerging landscape of molecular interaction networks: Opportunities, challenges and prospects
Network biology finds application in interpreting molecular interaction networks and
providing insightful inferences using graph theoretical analysis of biological systems. The …
providing insightful inferences using graph theoretical analysis of biological systems. The …
[HTML][HTML] Towards a dynamic interaction network of life to unify and expand the evolutionary theory
E Bapteste, P Huneman - BMC biology, 2018 - Springer
The classic Darwinian theory and the Synthetic evolutionary theory and their linear models,
while invaluable to study the origins and evolution of species, are not primarily designed to …
while invaluable to study the origins and evolution of species, are not primarily designed to …
Asymmetric evolution of protein domains in the leucine-Rich repeat receptor-like kinase family of plant signaling proteins
J Man, TA Harrington, K Lally… - Molecular Biology and …, 2023 - academic.oup.com
The coding sequences of developmental genes are expected to be deeply conserved, with
cis-regulatory change driving the modulation of gene function. In contrast, proteins with roles …
cis-regulatory change driving the modulation of gene function. In contrast, proteins with roles …
[HTML][HTML] Developmental phenomics suggests that H3K4 monomethylation confers multi-level phenotypic robustness
How histone modifications affect animal development remains difficult to ascertain. Despite
the prevalence of histone 3 lysine 4 monomethylation (H3K4me1) on enhancers …
the prevalence of histone 3 lysine 4 monomethylation (H3K4me1) on enhancers …
Molecular chaperones accelerate the evolution of their protein clients in yeast
D Alvarez-Ponce, J Aguilar-Rodríguez… - Genome biology and …, 2019 - academic.oup.com
Protein stability is a major constraint on protein evolution. Molecular chaperones, also
known as heat-shock proteins, can relax this constraint and promote protein evolution by …
known as heat-shock proteins, can relax this constraint and promote protein evolution by …
The effect of developmental pleiotropy on the evolution of insect immune genes
AM Williams, TM Ngo, VE Figueroa… - Genome biology and …, 2023 - academic.oup.com
The pressure to survive ever-changing pathogen exposure explains the frequent
observation that immune genes are among the fastest evolving in the genomes of many …
observation that immune genes are among the fastest evolving in the genomes of many …
[HTML][HTML] Whole-genome sequencing reveals that regulatory and low pleiotropy variants underlie local adaptation to environmental variability in purple sea urchins
Organisms experience environments that vary across both space and time. Such
environmental heterogeneity shapes standing genetic variation and may influence species' …
environmental heterogeneity shapes standing genetic variation and may influence species' …
[HTML][HTML] Rapid turnover of life-cycle-related genes in the brown algae
Background Sexual life cycles in eukaryotes involve a cyclic alternation between haploid
and diploid phases. While most animals possess a diploid life cycle, many plants and algae …
and diploid phases. While most animals possess a diploid life cycle, many plants and algae …
[HTML][HTML] Networks consolidate the core concepts of evolution by natural selection
F Papale, J Saget, É Bapteste - Trends in Microbiology, 2020 - cell.com
Microbiology has unraveled rich evidence of ongoing reticulate evolutionary processes and
complex interactions both within and between cells. These phenomena feature real …
complex interactions both within and between cells. These phenomena feature real …
[HTML][HTML] Elucidating the network features and evolutionary attributes of intra-and interspecific protein–protein interactions between human and pathogenic bacteria
Host–pathogen interaction is one of the most powerful determinants involved in
coevolutionary processes covering a broad range of biological phenomena at molecular …
coevolutionary processes covering a broad range of biological phenomena at molecular …