Three and a half years after the pandemic outbreak, now that WHO has formally declared
that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes post-
acute sequelae of coronavirus disease 2019 (COVID-19)(PASC) in many organ systems …

Introduction The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has posed
unprecedented global health challenges since its emergence in December 2019. The rapid …

Alternative splicing generates functional diversity in isoforms, impacting immune response to
infection. Here, we evaluate the causal role of alternative splicing in COVID-19 severity and …

SARS-CoV-2 has infected over 340 million people, prompting therapeutic research. While
genetic studies can highlight potential drug targets, understanding the heritability of SARS …

The COVID-19 pandemic has brought to light considerable clinical variation among
individuals infected with SARS-CoV-2, ranging from asymptomatic cases to fatal outcome …

The HostSeq initiative recruited 10,059 Canadians infected with SARS-CoV-2 between
March 2020 and March 2023, obtained clinical information on their disease experience and …

Human genetic studies of critical COVID-19 pneumonia have revealed the essential role of
type I interferon-dependent innate immunity to SARS-CoV-2 infection. Conversely, an …

The COVID-19 pandemic highlighted the importance of effective vaccination strategies in
controlling the spread of infectious diseases. SARS-CoV-2 vaccine has demonstrated high …

High levels of ADAM17 activity have emerged as an important mediator in severe COVID-
19. This study aims to characterize eventual causal relationships between ADAM17 and …