The benefits of regular physical activity are related to delaying and reversing the onset of
ageing and age-related disorders, including cardiomyopathy, neurodegenerative diseases …

The imaging-based method of brainAGE aims to characterize an individual's vulnerability to
age-related brain changes. The present study systematically reviewed brainAGE findings in …

Abstract The Dominantly Inherited Alzheimer Network (DIAN) is an international
collaboration studying autosomal dominant Alzheimer disease (ADAD). ADAD arises from …

Modeling spatiotemporal brain dynamics from high-dimensional data, such as functional
Magnetic Resonance Imaging (fMRI), is a formidable task in neuroscience. Existing …

China and the world are facing severe population aging and an increasing burden of age-
related diseases. Aging of the brain causes major age-related brain diseases, such as …

Identifying the clinical implications and modifiable and unmodifiable factors of aging
requires the measurement of biological age (BA) and age gap. Leveraging the biomedical …

Measuring differences between an individual's age and biological age with biological
information from the brain have the potential to provide biomarkers of clinically relevant …

Brain-age can be inferred from structural neuroimaging and compared to chronological age
(brain-age delta) as a marker of biological brain aging. Accelerated aging has been found in …

The difference between the estimated brain age and the chronological age ('brain-PAD')
could become a clinical biomarker. However, most brain age models were developed for …

Background “Brain-predicted age” estimates biological age from complex, nonlinear
features in neuroimaging scans. The brain age gap (BAG) between predicted and …