Gliomas are the most common central nervous system tumors. New technologies, including
genetic research and advanced statistical methods, revolutionize the therapeutic approach …

Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

The treatment of glioblastoma has limited clinical progress over the past decade, partly due
to the lack of effective drug delivery strategies across the blood-brain-tumor barrier …

Tumor microenvironment (TME) is the internal environment in which tumor cells survive,
consisting of tumor cells, fibroblasts, endothelial cells, and immune cells, as well as non …

Glioblastoma (GBM) is the most common and most aggressive brain tumour. Prognosis
remains poor, despite the combined treatment of radio-and chemotherapy following surgical …

Central nervous system (CNS) homeostasis critically depends on the interaction between
neurons and glia cells. Extracellular vesicles (EVs) recently emerged as versatile …

In the last two decades no significant advances were achieved in the treatment of the most
frequent and malignant types of brain tumors. The main difficulties in achieving progress are …

Using in vivo muscle stem cell (satellite cell)-specific extracellular vesicle (EV) tracking,
satellite cell depletion, in vitro cell culture, and single-cell RNA sequencing, we show …

Glioblastoma the most aggressive form of brain cancer, comprises a complex mixture of
tumor cells and nonmalignant stromal cells, including neurons, astrocytes, microglia …

Despite considerable recent advances in understanding and treating many other cancers,
malignant brain tumors remain associated with low survival or severe long-term sequelae …