Potentiating hypoxic microenvironment for antibiotic activation by photodynamic therapy to combat bacterial biofilm infections

W Xiu, L Wan, K Yang, X Li, L Yuwen, H Dong… - Nature …, 2022 - nature.com
Traditional antibiotic treatment has limited efficacy for the drug-tolerant bacteria present in
biofilms because of their unique metabolic conditions in the biofilm infection …

Photodynamic chitosan functionalized MoS2 nanocomposite with enhanced and broad-spectrum antibacterial activity

W Cao, L Yue, Y Zhang, Z Wang - Carbohydrate Polymers, 2022 - Elsevier
Bacterial infection accompanied by antibiotic resistance leads to the lack of effective
antibacterial agents, which has become an imminent problem afflicting people. Therefore …

Functionalized Cu 3 BiS 3 nanoparticles for dual-modal imaging and targeted photothermal/photodynamic therapy

Y Wang, D Cai, H Wu, Y Fu, Y Cao, Y Zhang, D Wu… - Nanoscale, 2018 - pubs.rsc.org
Multifunctional nano-biomaterials with the integration of diagnostic and therapeutic functions
have shown great promise in improving the efficacy of cancer therapy. Herein, a new …

In vitro study: green synthesis and evaluation of MgO/C-dots/DOX phosphorescent nanocomposites for photodynamic/photocatalytic therapy of tumors

M Karimi, E Sadeghi, M Zahedifar, M Nejati… - … in Bioengineering and …, 2023 - frontiersin.org
MgO nanoparticles (NPs) and carbon dots (C-dots) were synthesized by co-precipitation and
hydrothermal techniques. In the next step, as-synthesized NPs were modified by C-dots …

EGF-conjugated bio-safe luteolin gold nanoparticles induce cellular toxicity and cell death mediated by site-specific rapid uptake in human triple negative breast …

S Mal, T Saha, A Halder, SK Paidesetty, S Das… - Journal of Drug Delivery …, 2023 - Elsevier
Abstract World Health Organization listed breast cancer as the most prevalent form of cancer
in recent times. Triple negative breast cancer is its deadliest sub-type characterized by high …

Chlorin e6-EGF conjugated gold nanoparticles as a nanomedicine based therapeutic agent for triple negative breast cancer

ML Castilho, VPS Jesus, PFA Vieira, KC Hewitt… - Photodiagnosis and …, 2021 - Elsevier
To develop a treatment modality for triple-negative breast cancer, we investigated the
efficacy of a bifunctional theranostic nanoprobes (BN) during Photodynamic Therapy (PDT) …

Gold-coated superparamagnetic iron oxide nanoparticles functionalized to EGF and Ce6 complexes for breast cancer diagnoses and therapy

M Cândido, P Vieira, A Campos, C Soares, L Raniero - Pharmaceutics, 2022 - mdpi.com
Superparamagnetic iron oxide nanoparticles (SPIONs) have some limitations in the
physiological environment, however, a modification on their surface, such as a core–shell …

Nanoparticles of methylene blue enhance photodynamic therapy

VPS Jesus, L Raniero, GM Lemes… - Photodiagnosis and …, 2018 - Elsevier
Breast cancer is the most commonly diagnosed cancer and the second leading cause of
death related to cancer among women worldwide. Screening and advancements in …

Metabolic Modulation-Mediated Antibiotic and Immune Activation for Treatment of Chronic Lung Infections

W Xiu, H Dong, X Chen, L Wan, L Lu, K Yang… - ACS …, 2024 - ACS Publications
The Pseudomonas aeruginosa biofilm in recalcitrant chronic lung infections not only
develops high antimicrobial tolerance but also induces an aberrant host inflammatory …

Antibacterial activity of silver nanoparticles functionalized with amikacin applied against multidrug-resistant Acinetobacter baumannii

LO Camargo, I Fontoura, TS Veriato, L Raniero… - American Journal of …, 2023 - Elsevier
Background Multidrug-resistant bacteria are one of the world's biggest health problems;
therefore, improving the spectrum of action of antibiotics could be necessary to reverse this …