Modeling and simulation of rat non-barrel somatosensory cortex. part i: Modeling anatomy

MW Reimann, S Bolaños-Puchet, JD Courcol… - bioRxiv, 2022 - biorxiv.org
The function of the neocortex is fundamentally determined by its repeating microcircuit motif,
but also by its rich, hierarchical, interregional structure with a highly specific laminar …

Efficiency and reliability in biological neural network architectures

DE Santander, C Pokorny, A Ecker, J Lazovskis… - bioRxiv, 2024 - biorxiv.org
Neurons in a neural circuit exhibit astonishing diversity in terms of the numbers and targets
of their synaptic connections and the statistics of their spiking activity. We hypothesize that …

Heterogeneous and higher-order cortical connectivity undergirds efficient, robust, and reliable neural codes

DE Santander, C Pokorny, A Ecker, J Lazovskis… - iScience, 2025 - cell.com
We hypothesized that the heterogeneous architecture of biological neural networks provides
a substrate to regulate the well-known tradeoff between robustness and efficiency, thereby …