Post-COVID-19 depressive symptoms: epidemiology, pathophysiology, and pharmacological treatment

MG Mazza, M Palladini, S Poletti, F Benedetti - CNS drugs, 2022 - Springer
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic is still spreading worldwide
over 2 years since its outbreak. The psychopathological implications in COVID-19 survivors …

Immunosenescence and inflammaging in the aging process: age-related diseases or longevity?

A Santoro, E Bientinesi, D Monti - Ageing research reviews, 2021 - Elsevier
During aging the immune system (IS) undergoes remarkable changes that collectively are
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …

Inflammation, Aging, and Cardiovascular Disease: JACC Review Topic of the Week

L Liberale, L Badimon, F Montecucco… - Journal of the American …, 2022 - jacc.org
Aging and inflammation both contribute pivotally to cardiovascular (CV) and cerebrovascular
disease, the leading causes of death and disability worldwide. The concept of inflamm-aging …

miR-21 and miR-146a: the microRNAs of inflammaging and age-related diseases

F Olivieri, F Prattichizzo, A Giuliani… - Ageing research …, 2021 - Elsevier
The first paper on “inflammaging” published in 2001 paved the way for a unifying theory on
how and why aging turns out to be the main risk factor for the development of the most …

Inflammaging and 'Garb-aging'

C Franceschi, P Garagnani, G Vitale, M Capri… - Trends in Endocrinology …, 2017 - cell.com
'Inflammaging'refers to the chronic, low-grade inflammation that characterizes aging.
Inflammaging is macrophage centered, involves several tissues and organs, including the …

One-year mental health outcomes in a cohort of COVID-19 survivors

MG Mazza, M Palladini, R De Lorenzo, B Bravi… - Journal of psychiatric …, 2022 - Elsevier
COVID-19 survivors are at increased risk of persistent psychopathology after the infection.
Despite long-term sequelae are an increasing concern, long-term neuropsychiatric …

Aging and Parkinson's Disease: Inflammaging, neuroinflammation and biological remodeling as key factors in pathogenesis

V Calabrese, A Santoro, D Monti, R Crupi… - Free Radical Biology …, 2018 - Elsevier
In order to better understand the pathogenesis of Parkinson's Disease (PD) it is important to
consider possible contributory factors inherent to the aging process, as age-related changes …

Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes

M Bonafè, F Prattichizzo, A Giuliani, G Storci… - Cytokine & Growth …, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is characterized
by a high mortality of elderly men with age-related comorbidities. In most of these patients …

[HTML][HTML] The hormetic and hermetic role of IL-6

L Forcina, C Franceschi, A Musarò - Ageing research reviews, 2022 - Elsevier
Interleukin-6 is a pleiotropic cytokine regulating different tissues and organs in diverse and
sometimes discrepant ways. The dual and sometime hermetic nature of IL-6 action has been …

Aging, inflammation, immunity and periodontal disease

JL Ebersole, CL Graves, OA Gonzalez… - Periodontology …, 2016 - Wiley Online Library
The increased prevalence and severity of periodontal disease have long been associated
with aging, such that this oral condition affects the majority of the adult population over 50 …