State-of-the-art application of artificial intelligence to transporter-centered functional and pharmaceutical research
Protein transporters not only have essential functions in regulating the transport of
endogenous substrates and remote communication between organs and organisms, but …
endogenous substrates and remote communication between organs and organisms, but …
Recent advances in features generation for membrane protein sequences: From multiple sequence alignment to pre‐trained language models
Membrane proteins play a crucial role in various cellular processes and are essential
components of cell membranes. Computational methods have emerged as a powerful tool …
components of cell membranes. Computational methods have emerged as a powerful tool …
TRP-BERT: Discrimination of transient receptor potential (TRP) channels using contextual representations from deep bidirectional transformer based on BERT
SMA Shah, YY Ou - Computers in Biology and Medicine, 2021 - Elsevier
Transient receptor potential (TRP) channels are non-selective cation channels that act as
ion channels and are primarily found on the plasma membrane of numerous animal cells …
ion channels and are primarily found on the plasma membrane of numerous animal cells …
Integrating Pre-Trained protein language model and multiple window scanning deep learning networks for accurate identification of secondary active transporters in …
Secondary active transporters play pivotal roles in regulating ion and molecule transport
across cell membranes, with implications in diseases like cancer. However, studying …
across cell membranes, with implications in diseases like cancer. However, studying …
Identification of efflux proteins based on contextual representations with deep bidirectional transformer encoders
Efflux proteins are the transport proteins expressed in the plasma membrane, which are
involved in the movement of unwanted toxic substances through specific efflux pumps …
involved in the movement of unwanted toxic substances through specific efflux pumps …
Data-driven technology roadmaps to identify potential technology opportunities for hyperuricemia drugs
L Feng, W Zhao, J Wang, KY Lin, Y Guo, L Zhang - Pharmaceuticals, 2022 - mdpi.com
Hyperuricemia is a metabolic disease with an increasing incidence in recent years. It is
critical to identify potential technology opportunities for hyperuricemia drugs to assist drug …
critical to identify potential technology opportunities for hyperuricemia drugs to assist drug …