The unusual regenerative properties of the liver are a logical adaptation by organisms, as
the liver is the main detoxifying organ of the body and is likely to be injured by ingested …

Ageing is the biggest risk factor for impaired cardiovascular health, with cardiovascular
disease being the cause of death in 40% of individuals over 65 years old. Ageing is …

Objectives: To assess safety and outcomes of the novel 2-stage hepatectomy, Associating
Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS), using an …

The liver possesses the unique ability to regenerate within a short period of time, a feature
that has led to the development of innovative strategies in liver surgery and transplantation …

The liver can precisely regulate its growth and mass. Surgical resection of hepatic lobes or
hepatocyte loss caused by viral or chemical injury triggers hepatocyte replication while …

The liver can regenerate its volume after major tissue loss. In a mouse model of liver
regeneration, thrombocytopenia, or impaired platelet activity resulted in the failure to initiate …

Widespread application of cadaveric split or living donor liver transplantation bears
considerable potential to increase the pool of available organs and thus alleviate the …

Steatosis of the liver is common in Western countries, affecting about 25% of donors for liver
transplantation and 20% of patients undergoing liver resection. Transplantation of livers with …

Hepatic steatosis is associated with significant morbidity and mortality after liver resection
and transplantation. Although apoptosis is a key mechanism of reperfusion injury in the …

Hepatic resection or transplantation in patients with fatty liver is associated with increased
morbidity and mortality. The regenerative capacity of fatty livers after major tissue loss is …