It is now clear that there is a diversity of circular RNAs in biological systems. Circular RNAs
can be produced by the direct ligation of 5′ and 3′ ends of linear RNAs, as intermediates …

Homing endonucleases are encoded by open reading frames that are embedded within
group I, group II and archael introns, as well as inteins (intervening sequences that are …

The study of genomic organization and regulatory elements of rRNA genes in metazoan
paradigmatic organisms has led to the most accepted model of rRNA gene organization in …

Group I introns are genetic elements interrupting functional genes. They are removed from
precursors at the RNA level and most catalyze their own splicing. The catalytic part of these …

New evidence indicates that termination of transcription is an important regulatory step,
closely related to transcriptional interference and even transcriptional initiation. However …

Plasmodial slime molds are members of the class Amoebozoa forming elaborate fruit bodies
releasing airborne spores. Two species concepts have been developed independently: a …

Twin-ribozyme introns are formed by two ribozymes belonging to the group I family and
occur in some ribosomal RNA transcripts. The group I-like ribozyme, GIR1, liberates the 5 …

The lariat-capping (LC) ribozyme is a natural ribozyme isolated from eukaryotic
microorganisms. Despite apparent structural similarity to group I introns, the LC ribozyme …

Group I introns are a distinct class of RNA self-splicing introns with an ancient origin. All
known group I introns present in eukaryote nuclei interrupt functional ribosomal RNA genes …

In addition to splicing, group I intron RNA is capable of an alternative two-step processing
pathway that results in the formation of full-length intron circular RNA. The circularization …