Bipolar disorder is a recurrent chronic disorder characterised by fluctuations in mood state
and energy. It affects more than 1% of the world's population irrespective of nationality …

Bipolar disorder refers to a group of affective disorders, which together are characterised by
depressive and manic or hypomanic episodes. These disorders include: bipolar disorder …

We performed a quantitative review of associations between the higher order personality
traits in the Big Three and Big Five models (ie, neuroticism, extraversion, disinhibition …

OBJECTIVE: To qualitatively review the literature of the past decade covering the
epidemiology, clinical characteristics, natural course, biology, and other correlates of early …

Background To our knowledge, this is the first prospective natural history study of weekly
symptomatic status of patients with bipolar I disorder (BP-I) during long-term follow-up …

Background This is the first prospective longitudinal study, to our knowledge, of the natural
history of the weekly symptomatic status of bipolar II disorder (BP-II). Methods Weekly …

A revision of the 2008 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken in order to …

Until recently it was believed that no more than 1% of the general population has bipolar
disorder. Emerging transatlantic data are beginning to provide converging evidence for a …

This article describes the bipolar spectrum in a historical32 and conceptual context, 2 then
provides clinical descriptions for subtypes within this spectrum. Through case material, the …

BACKGROUND: Our aim was to validate the Temperament Evaluation of the Memphis, Pisa,
Paris, and San Diego Autoquestionnaire (TEMPS-A) in a clinical population. METHODS …