Sulfated polysaccharides: Immunomodulation and signaling mechanisms

L Huang, M Shen, GA Morris, J Xie - Trends in Food Science & Technology, 2019 - Elsevier
Background Polysaccharides are natural macromolecular polymers that are widely
distributed in various food resources and have attracted much attention due to their …

The mannose receptor

L Martinez-Pomares - Journal of leukocyte biology, 2012 - academic.oup.com
Review on mannose receptor as an endocytic receptor in antigen delivery that is co-
expressed with the microRNA miR-511-3p encoded within the Mrc1 gene. The MR is a …

A programmable encapsulation system improves delivery of therapeutic bacteria in mice

T Harimoto, J Hahn, YY Chen, J Im, J Zhang… - Nature …, 2022 - nature.com
Living bacteria therapies have been proposed as an alternative approach to treating a broad
array of cancers. In this study, we developed a genetically encoded microbial encapsulation …

The Pseudomonas aeruginosa lectin LecB binds to the exopolysaccharide Psl and stabilizes the biofilm matrix

D Passos da Silva, ML Matwichuk… - Nature …, 2019 - nature.com
Pseudomonas aeruginosa biofilms are composed of exopolysaccharides (EPS), exogenous
DNA, and proteins that hold these communities together. P. aeruginosa produces lectins …

Engineered probiotics biofilm enhances osseointegration via immunoregulation and anti-infection

L Tan, J Fu, F Feng, X Liu, Z Cui, B Li, Y Han… - Science …, 2020 - science.org
Preventing multidrug-resistant bacteria–related infection and simultaneously improving
osseointegration are in great demand for orthopedic implants. However, current strategies …

Pattern recognition receptors: doubling up for the innate immune response

S Gordon - Cell, 2002 - cell.com
Antigen presenting cells (macrophages and dendritic cells) express pattern recognition
molecules that are thought to recognize foreign ligands during early phases of the immune …

Macrophage activation markers, CD163 and CD206, in acute-on-chronic liver failure

MC Nielsen, R Hvidbjerg Gantzel, J Clària, J Trebicka… - Cells, 2020 - mdpi.com
Macrophages facilitate essential homeostatic functions eg, endocytosis, phagocytosis, and
signaling during inflammation, and express a variety of scavenger receptors including …

Influence of the mannose receptor in host immune responses

U Gazi, L Martinez-Pomares - Immunobiology, 2009 - Elsevier
Mannose receptor (MR) is a C-type lectin primarily expressed by macrophages and dendritic
cells. Its three distinct extracellular binding sites recognise a wide range of both endogenous …

Toll-like receptor 4-related immunostimulatory polysaccharides: Primary structure, activity relationships, and possible interaction models

X Zhang, C Qi, Y Guo, W Zhou, Y Zhang - Carbohydrate polymers, 2016 - Elsevier
Abstract Toll-like receptor (TLR) 4 is an important polysaccharide receptor; however, the
relationships between the structures and biological activities of TLR4 and polysaccharides …

A review on macrophage responses to biomaterials

Z Xia, JT Triffitt - Biomedical materials, 2006 - iopscience.iop.org
Macrophages are the dominant infiltrating cells that respond rapidly to biomaterial
implantation in soft and hard tissues. These cells and their fused morphologic variants …