Metal compounds against neglected tropical diseases

YC Ong, S Roy, PC Andrews, G Gasser - Chemical reviews, 2018 - ACS Publications
Many first-line treatments for neglected tropical diseases identified by the World Health
Organization (WHO) are limited by one or more of the following: the development of drug …

Metal complexes of [1, 2, 4] triazolo-[1, 5-a] pyrimidine derivatives

JM Salas, MA Romero, MP Sánchez… - Coordination Chemistry …, 1999 - Elsevier
This article covers all the research work published until September 1998 about the
coordination chemistry of 1, 2, 4-triazolo-[1, 5-a] pyrimidine derivatives. The revision is …

Synthesis and antitumor activity of substituted triazolo [4, 3-a] pyrimidin-6-sulfonamide with an incorporated thiazolidinone moiety

HN Hafez, ARBA El-Gazzar - Bioorganic & medicinal chemistry letters, 2009 - Elsevier
Chlorosulfonation of 3-methyl [1, 2, 4] triazolo [4, 3-a] pyrimidine with chlorosulfonic acid in
the presence of thionyl chloride was studied. When triazolo [4, 3-a] pyrimidines are used as …

[HTML][HTML] Immobilized sulfonic acid functionalized ionic liquid on magnetic cellulose as a novel catalyst for the synthesis of triazolo [4, 3-a] pyrimidines

A Jahanbakhshi, M Farahi - Arabian Journal of Chemistry, 2022 - Elsevier
The Brønsted acidic ionic liquid 1-(propyl-3-sulfonate) vinyl imidazolium hydrogen sulfate
[IL] was supported on modified magnetic cellulose. The physical structure, composition, and …

Triazolopyrimidine compounds containing first-row transition metals and their activity against the neglected infectious Chagas disease and leishmaniasis

AB Caballero, A Rodríguez-Diéguez, M Quirós… - European journal of …, 2014 - Elsevier
Leishmaniasis and Chagas disease remain a significant global problem. Current treatments
have serious disadvantage due to cost, toxicity, long therapy duration and resistance. In the …

[HTML][HTML] Synthesis and anticancer activity of some fused pyrimidines and related heterocycles

SA Al-Issa - Saudi Pharmaceutical Journal, 2013 - Elsevier
On account of the reported anticancer of pyrimidine and condensed pyrimidine, a new
pyrimido [3, 2-b]-1, 2, 4, 5-tetrazine 3a, b, 5c, d, 6, 9, pyrimido [3, 2-b]-1, 2, 4-triazine 10, 11 …

Silica-coated magnetic nanoparticles containing bis dicationic bridge for the synthesis of 1, 2, 4-triazolo pyrimidine/quinazolinone derivatives

R Karimi-Chayjani, N Daneshvar… - Journal of Molecular …, 2020 - Elsevier
In this work and for the first time, the preparation of bis-[(3-aminopropyl) triethoxysilane]
dichloride immobilized on magnetic nano γ-Fe 2 O 3@ SiO 2 via the reaction of two …

Synthesis, antitumor activity and structure–activity relationships of a series of Ru (II) complexes

J Liu, W Zheng, S Shi, C Tan, J Chen, K Zheng… - Journal of inorganic …, 2008 - Elsevier
A series of octahedral Ru (II) polypyridyl complexes,[Ru (phen) 2L] 2+(L= R-PIP and PIP= 2-
phenylimidazo [4, 5-f][1, 10] phenanthroline) were synthesized and characterized by …

Synthesis and antimicrobial evaluation of novel triazole, tetrazole, and spiropyrimidine-thiadiazole derivatives

AA Abu-Hashem, M El-Shazly - Polycyclic Aromatic Compounds, 2021 - Taylor & Francis
The aim of the present work was the synthesis of some new heterocyclic compounds derived
from 6-(2, 4-dimethyl-3H-benzo [f][Citation 1, Citation 3, Citation 5] triazepin-3-yl)-2-thioxo-2 …

Synthesis of novel 1, 2, 4-triazolopyrimidines and their evaluation as antimicrobial agents

AA Abu-Hashem, HAR Hussein… - Medicinal Chemistry …, 2017 - Springer
aminopyrimidin-5 (1 H)-one (5) was utilized as a starting material for the preparation of new,
Schiff bases (13–19), amides 23, 24, imide 25, as well as thiourea derivatives 30–33 …