A Domańska, A Orzechowski… - Oxidative Medicine …, 2021 - Wiley Online Library
Alzheimer's disease (AD) is the most common form of dementia with a growing incidence rate primarily among the elderly. It is a neurodegenerative, progressive disorder leading to …
I Ferrer - International Journal of Molecular Sciences, 2024 - mdpi.com
Human brain aging is characterized by the production and deposition of β-amyloid (Aβ) in the form of senile plaques and cerebral amyloid angiopathy and the intracellular …
A Gołaszewska, W Bik, T Motyl… - International journal of …, 2019 - mdpi.com
The average life span steadily grows in humans and in animals kept as pets or left in sanctuaries making the issue of elderly-associated cognitive impairment a hot-spot for …
Alzheimer's disease (AD) is one of the leading causes of dementia in late life. Although the cause of AD neurodegenerative changes is not fully understood, extensive evidence …
D De Biase, A Costagliola, TB Pagano, G Piegari… - BMC veterinary …, 2017 - Springer
Background Autophagy is a highly regulated process involving the bulk degradation of cytoplasmic macromolecules and organelles in mammalian cells via the lysosomal system …
K Orekhova, C Testori, F Giorda, C Grattarola… - PloS one, 2024 - journals.plos.org
Cetacean brains are uniquely adapted to diving, but can be affected by diseases and exposure to toxins, triggering neurodegenerative processes that may cause stranding. Some …
B Schwehr, D Hartnell, G Ellison, M Hindes, B Milford… - Analyst, 2024 - pubs.rsc.org
Neurobiological research relies heavily on imaging techniques, such as fluorescence microscopy, to understand neurological function and disease processes. However, the …
Simple Summary Brain aging in mammals is characterized by morphological and functional changes in neural cells. This process, although physiological, leads to progressive cerebral …
AJ Malbon, L Sordo, LA Wilson, D Gunn-Moore… - Neurobiology of …, 2022 - Elsevier
Neurodegenerative disorders are gaining ever more importance in ageing populations of animals and people. Altered insulin signaling and type II diabetes have been linked to the …