L-Asparaginase (ASNase) is a vital component of the first line treatment of acute
lymphoblastic leukemia (ALL), an aggressive type of blood cancer expected to afflict over …

Abstract L-Asparaginase (L-ASNase, EC 3.5. 1.1), an antitumor drug for acute lymphoblastic
leukemia (ALL) therapy, is widely used in the clinical field. Similarly, L-ASNase is also a …

Metabolic differences between normal and cancerous cells have been used as a point of
view for developing anticancer drugs. Some degrading enzymes of certain amino acids …

Abstract l-Asparaginases (EC 3.5. 1.1) are enzymes that catalyze the hydrolysis of l-
asparagine to l-aspartic acid and found in a variety of organisms from microorganisms to …

Purpose The benefits of asparaginase (ASNASE) in the treatment of ALL and NHL are
indisputable and new ASNASE preparations are under clinical development to overcome …

L-asparaginase is one of the protein drugs for countering leukemia and lymphoma. A major
challenge in the therapeutic potential of the enzyme is its immunogenicity, low-plasma half …

L-asparaginase is an important enzyme in the pharmaceutical field used as treatment for
acute lymphoblastic leukemia due to its ability to hydrolyze L-asparagine, an essential …

Genetic engineering for heterologous expression has advanced in recent years. Model
systems such as Escherichia coli, Bacillus subtilis and Pichia pastoris are often used as host …

Cancer remains a persistent global health concern, representing a significant challenge in
medical science and patient care. In this context, l‐asparaginase has emerged as a …

Abstract β-Galactosidase enzymes continue to play an important role in food and
pharmaceutical industries. These enzymes hydrolyze lactose in its constituent …