[HTML][HTML] Current antifungal drugs and immunotherapeutic approaches as promising strategies to treatment of fungal diseases

S Nami, A Aghebati-Maleki, H Morovati… - Biomedicine & …, 2019 - Elsevier
Invasive candidiasis (IC) can affect individuals with various underlying diseases hospitalized
in different parts of hospitals. In recent decades, IC has caused 27–55% mortality in general …

dsRNA uptake in plant pests and pathogens: insights into RNAi-based insect and fungal control technology

N Wytinck, CL Manchur, VH Li, S Whyard, MF Belmonte - Plants, 2020 - mdpi.com
Efforts to develop more environmentally friendly alternatives to traditional broad-spectrum
pesticides in agriculture have recently turned to RNA interference (RNAi) technology. With …

Improving RNA-based crop protection through nanotechnology and insights from cross-kingdom RNA trafficking

A Chen, L Halilovic, JH Shay, A Koch, N Mitter… - Current opinion in plant …, 2023 - Elsevier
Spray-induced gene silencing (SIGS) is a powerful and eco-friendly method for crop
protection. Based off the discovery of RNA uptake ability in many fungal pathogens, the …

RNA interference strategies for future management of plant pathogenic fungi: Prospects and challenges

DE Gebremichael, ZM Haile, F Negrini, S Sabbadini… - Plants, 2021 - mdpi.com
Plant pathogenic fungi are the largest group of disease-causing agents on crop plants and
represent a persistent and significant threat to agriculture worldwide. Conventional …

Clathrin mediated endocytosis is involved in the uptake of exogenous double-stranded RNA in the white mold phytopathogen Sclerotinia sclerotiorum

N Wytinck, DS Sullivan, KT Biggar, L Crisostomo… - Scientific reports, 2020 - nature.com
RNA interference (RNAi) technologies have recently been developed to control a growing
number of agronomically significant fungal phytopathogens, including the white mold …

Investigation of multiple resistance mechanisms in voriconazole-resistant Aspergillus flavus clinical isolates from a chest hospital surveillance in Delhi, India

C Sharma, R Kumar, N Kumar, A Masih… - Antimicrobial Agents …, 2018 - Am Soc Microbiol
Invasive and allergic infections by Aspergillus flavus are more common in tropical and
subtropical countries. The emergence of voriconazole (VRC) resistance in A. flavus impacts …

Magnitude of voriconazole resistance in clinical and environmental isolates of Aspergillus flavus and investigation into the role of multidrug efflux pumps

RA Paul, SM Rudramurthy, M Dhaliwal… - Antimicrobial agents …, 2018 - Am Soc Microbiol
The magnitude of azole resistance in Aspergillus flavus and its underlying mechanism is
obscure. We evaluated the frequency of azole resistance in a collection of clinical (n= 121) …

Disruption of the Aspergillus fumigatus RNA interference machinery alters the conidial transcriptome

AA Kelani, A Bruch, F Rivieccio, C Visser, T Krüger… - RNA, 2023 - rnajournal.cshlp.org
The RNA interference (RNAi) pathway has evolved numerous functionalities in eukaryotes,
with many on display in Kingdom Fungi. RNAi can regulate gene expression, facilitate drug …

Genome-wide mRNA and miRNA analysis in the early stages of germ tube outgrowth in Coprinopsis cinerea

AYT Lau, Y Xie, MK Cheung, PCK Cheung… - Fungal Genetics and …, 2020 - Elsevier
Coprinopsis cinerea is a model mushroom-forming basidiomycete which produces
basidiospores during sexual reproduction. This fungus is widely used to study fruiting body …

[HTML][HTML] An appraisal of antifungal impacts of nano-liposome containing voriconazole on voriconazole-resistant Aspergillus flavus isolates as a groundbreaking drug …

P Hassanpour, H Hamishehkar… - Nanomedicine …, 2020 - nanomedicine-rj.com
Background: This study is an attempt to investigate the effect of nano-liposome containing
voriconazole on voriconazole-resistant A. flavus strains on the one hand, and to consider the …