An overview of the antioxidant effects of ascorbic acid and alpha lipoic acid (in liposomal forms) as adjuvant in cancer treatment

M Attia, EA Essa, RM Zaki, AA Elkordy - Antioxidants, 2020 - mdpi.com
Antioxidants are known to minimize oxidative stress by interacting with free radicals
produced as a result of cell aerobic reactions. Oxidative stress has long been linked to many …

Understanding the therapeutic potential of ascorbic acid in the battle to overcome cancer

J Reang, PC Sharma, VK Thakur, J Majeed - Biomolecules, 2021 - mdpi.com
Cancer, a fatal disease, is also one of the main causes of death worldwide. Despite various
developments to prevent and treat cancer, the side effects of anticancer drugs remain a …

How to treat melanoma? the current status of innovative nanotechnological strategies and the role of minimally invasive approaches like PTT and PDT

J Lopes, CMP Rodrigues, MM Gaspar, CP Reis - Pharmaceutics, 2022 - mdpi.com
Melanoma is the most aggressive type of skin cancer, the incidence and mortality of which
are increasing worldwide. Its extensive degree of heterogeneity has limited its response to …

Ascorbic acid-loaded gliadin nanoparticles as a novel nutraceutical formulation

S Voci, A Gagliardi, M Fresta, D Cosco - Food Research International, 2022 - Elsevier
Ascorbic acid (AA) is one of the foremost antioxidants. Unfortunately, its sensitivity to
different external stimuli such as light, heat and oxygen are concrete limitations for its use …

Nanocarrier-based drug delivery for melanoma therapeutics

M Song, C Liu, S Chen, W Zhang - International Journal of Molecular …, 2021 - mdpi.com
Melanoma, as a tumor cell derived from melanocyte transformation, has the characteristics
of malignant proliferation, high metastasis, rapid recurrence, and a low survival rate …

Liposomal formulation of a new antifungal hybrid compound provides protection against Candida auris in the ex vivo skin colonization model

A Jaromin, R Zarnowski, A Markowski… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
The newly emerged pathogen, Candida auris, presents a serious threat to public health
worldwide. This multidrug-resistant yeast often colonizes and persists on the skin of patients …

Targeted delivery of combination therapeutics using monoclonal antibody 2C5-modified immunoliposomes for cancer therapy

R Narayanaswamy, VP Torchilin - Pharmaceutical research, 2021 - Springer
Purpose To develop immunoliposomes modified with monoclonal cancer-specific antibody
(mAb) 2C5 and co-loaded with a combination of two chemotherapeutics, in order to …

Carrier‐Free Delivery of Ultrasmall π‐Conjugated Oligomer Nanoparticles with Photothermal Conversion over 80% for Cancer Theranostics

R Zheng, Q Zhao, W Qing, S Li, Z Liu, Q Li, Y Huang - Small, 2022 - Wiley Online Library
High‐performance photothermal theranostics is urgently desired for cancer therapy because
of their good controllability and noninvasive features. The relatively low photothermal …

The Conjugates of Indolo[2,3-b]quinoline as Anti-Pancreatic Cancer Agents: Design, Synthesis, Molecular Docking and Biological Evaluations

M Cybulski, K Sidoryk, M Zaremba-Czogalla… - International Journal of …, 2024 - mdpi.com
New amide conjugates of hydroxycinnamic acids (HCAs) and the known antineoplastic 5, 11-
dimethyl-5 H-indolo [2, 3-b] quinoline (DiMIQ), an analog of the natural alkaloid …

Co-encapsulation of mitoxantrone and β-elemene in solid lipid nanoparticles to overcome multidrug resistance in leukemia

K Amerigos Daddy JC, M Chen, F Raza, Y Xiao, Z Su… - Pharmaceutics, 2020 - mdpi.com
Multidrug resistance (MDR) due to P-glycoprotein (P-gp) overexpression is a major obstacle
to successful leukemia chemotherapy. The combination of anticancer chemotherapy with a …