Oxidative stress has been linked to various disease states as well as physiological aging.
The lungs are uniquely exposed to a highly oxidizing environment and have evolved several …

The ICU patient with burns, neurotrauma, sepsis, or major surgery typifies the classic
hypermetabolic patient. These patients have increased energy and nutrient needs as a …

Carnosine is a natural endogenous dipeptide widely distributed in mammalian tissues,
existing at particularly high concentrations in the muscles and brain and possesses well …

Diets high in flavonoids have long been associated with nutritional recommendations, a
healthy lifestyle, and the prevention of chronic diseases. However, identification of specific …

We hypothesized that 4 wk of dietary nitrate supplementation would enhance exercise
performance and muscle metabolic adaptations to sprint interval training (SIT). Thirty-six …

This study was designed to determine whether the relaxant effect of apigenin was
endothelium dependent and to examine the possible antiproliferative effect of apigenin …

Aging is a major risk factor for the development of cardiovascular disease. Despite a
significant reduction in the mortality and morbidity rates over the last decade, the socio …

This investigation was aimed to provide a pharmacologic basis to the medicinal use of
Acorus calamus in cardiovascular disorders. In normotensive anesthetized rats, crude …

Purpose This study seeks to develop a liposomal formulation of diethylenetriamine
NONOate (DN), a long acting nitric oxide (NO) donor, with a goal to replace inhaled NO …

Despite advancements in disease management, sickle cell nephropathy, a major contributor
to mortality and morbidity in patients, has limited therapeutic options. Previous studies …