This chapter summarizes a number of factors that control the``input–output''function across
the motoneurons (MNs) comprising a single spinal motor nucleus. The main focus is on …

The objective of this project was to examine the influence of stimulus waveform and
frequency on extracellular stimulation of neurons with their cell bodies near the electrode …

Since 2000, there has been rapid acceleration in the use of tDCS in both clinical and
cognitive neuroscience research, encouraged by the simplicity of the technique (two …

Electrophysiological and computational evidence indicate that the excitatory current from the
synapses on the somato‐dendritic membrane is not large enough to drive the motoneurones …

In a rat corticostriatal slice, brief, suprathreshold, repetitive cortical stimulation evoked long‐
lasting plateau potentials in neostriatal neurons. Plateau potentials were often followed by …

In the presence of neuromodulators such as serotonin and noradrenaline, motoneurons
exhibit persistent inward currents (PICs) that serve to amplify synaptic inputs. A major …

A single spinal motoneuron receives tens of thousands of synapses. The neurotransmitters
released by many of these synapses act on iontotropic receptors and alter the driving …

Plateau potentials are generated by a voltage sensitive persistent inward current. In spinal
motoneurones this current is predominantly mediated by influx of Ca ei through L-type Ca …

Motor neurons translate synaptic input from widely distributed premotor networks into
patterns of action potentials that orchestrate motor unit force and motor behavior …

The ability of inhibitory synaptic inputs to dampen the excitability of motoneurons is
augmented when persistent inward currents (PICs) are activated. This amplification could be …