Clostridiodes difficile (C. difficile) was ranked an “urgent threat” by the Centers for Disease
Control and Prevention (CDC) in 2019. C. difficile infection (CDI) is the most common …

The microbiota inhabiting the intestinal tract provide several critical functions to its host.
Microorganisms found at the mucosal layer form organized three-dimensional structures …

How bacteria link their growth rate to external nutrient conditions is unknown. To investigate
how Bacillus subtilis cells alter the rate at which they expand their cell walls as they grow …

Most bacteria are surrounded by a cell wall that contains peptidoglycan (PG), a large
polymer composed of glycan strands held together by short peptide cross-links. There are …

Peptidoglycan (PG) is the main component of bacterial cell walls and the target for many
antibiotics. PG biosynthesis is tightly coordinated with cell wall growth and turnover, and …

Synthesis of capsular polysaccharide (CPS), an important virulence factor of pathogenic
bacteria, is modulated by the CpsBCD phosphoregulatory system in Streptococcus …

Clostridioides difficile (CD) is a Gram-positive, anaerobic bacterium that infects mainly
hospitalized and elderly people who have been treated with long-term antibiotic therapy …

It has been nearly three decades since the discovery of the first bacterial serine/threonine
protein kinase (STPK). Since then, a blend of technological advances has led to the …

Protein phosphorylation regulates a large variety of biological processes in all living cells. In
pathogenic bacteria, the study of serine, threonine, and tyrosine (Ser/Thr/Tyr) …

The anaerobic pathogen Clostridioides difficile is perfectly equipped to survive and persist
inside the mammalian intestine. When facing unfavorable conditions C. difficile is able to …