Application of electrospun drug-loaded nanofibers in cancer therapy

Y Yang, R Zhang, Z Liang, J Guo, B Chen, S Zhou… - Polymers, 2024 - mdpi.com
In the 21st century, chemotherapy stands as a primary treatment method for prevalent
diseases, yet drug resistance remains a pressing challenge. Utilizing electrospinning to …

Nano-based formulations of curcumin: Elucidating the potential benefits and future prospects in skin cancer

C Ratan, AM Arian, R Rajendran… - Biomedical …, 2023 - iopscience.iop.org
Skin cancer refers to any malignant lesions that occur in the skin and are observed
predominantly in populations of European descent. Conventional treatment modalities such …

Therapeutic potential of C2N as targeted drug delivery system for fluorouracil and nitrosourea to treat cancer: a theoretical study

F Ahsan, M Yar, A Gulzar, K Ayub - Journal of Nanostructure in Chemistry, 2023 - Springer
Conventional drug delivery systems suffer from poor absorption and poor bioavailability at
the target site due to either very weak or very strong adsorption of drug on the carrier …

Tuning the drug release from antibacterial polycaprolactone/rifampicin-based core–shell electrospun membranes: a proof of concept

M Gruppuso, B Guagnini, L Musciacchio… - … Applied Materials & …, 2022 - ACS Publications
The employment of coaxial fibers for guided tissue regeneration can be extremely
advantageous since they allow the functionalization with bioactive compounds to be …

Transforming cancer treatment with nanotechnology: the role of berberine as a star natural compound

L Sun, J Lan, Z Li, R Zeng, Y Shen… - International Journal of …, 2024 - Taylor & Francis
Berberine (BBR), recognized as an oncotherapeutic phytochemical, exhibits its anti-cancer
properties via multiple molecular pathways. However, its clinical application is hindered by …

Nedaplatin/Peganum harmala Alkaloids Co-Loaded Electrospun, Implantable Nanofibers: A Chemopreventive Nano-Delivery System for Treating and Preventing …

NK Sedky, KK Arafa, MMM Abdelhady, MY Issa… - Pharmaceutics, 2023 - mdpi.com
Currently, the main pillars in treating breast cancer involve tumorectomy pursued by
hormonal, radio, or chemotherapies. Nonetheless, these approaches exhibit severe adverse …

Near-Infrared Light-Responsive Nanofibrous Membranes for Treatment of Bacterial Wound Infections

W Lin, S Sun, D Zhang, Y Liu, J Yu, R Liu… - ACS Applied Nano …, 2023 - ACS Publications
Bacterial wound infections pose a significant challenge for both patients and healthcare
providers. To effectively treat bacterial wound infections, it is critical to develop functional …

[HTML][HTML] Electrospun poly-ε-caprolactone nanofibers incorporating keratin hydrolysates as innovative antioxidant scaffolds

NJ Clerici, AA Vencato, R Helm Júnior, DJ Daroit… - Pharmaceuticals, 2024 - mdpi.com
This manuscript describes the development and characterization of electrospun nanofibers
incorporating bioactive hydrolysates obtained from the microbial bioconversion of feathers, a …

Development and characterization of electrospun composites built on polycaprolactone and cerium-containing phases

C Plocon, A Evanghelidis, M Enculescu… - International Journal of …, 2023 - mdpi.com
The current study reports on the fabrication of composite scaffolds based on
polycaprolactone (PCL) and cerium (Ce)-containing powders, followed by their …

High dose, dual-release polymeric films for extended surgical bed paclitaxel delivery

DA Mahvi, J Korunes-Miller, C Bordeianu… - Journal of Controlled …, 2023 - Elsevier
While surgery represents a major therapy for most solid organ cancers, local recurrence is
clinically problematic for cancers such as sarcoma for which adjuvant radiotherapy and …