Global burden and epidemiology of Barrett oesophagus and oesophageal cancer

AP Thrift - Nature reviews Gastroenterology & hepatology, 2021 - nature.com
Oesophageal cancer is a global health problem; in 2018 there were more than 572,000
people newly diagnosed with oesophageal cancer worldwide. There are two main …

[HTML][HTML] The emerging role of cell-free DNA as a molecular marker for cancer management

AJ Bronkhorst, V Ungerer, S Holdenrieder - Biomolecular detection and …, 2019 - Elsevier
An increasing number of studies demonstrate the potential use of cell-free DNA (cfDNA) as a
surrogate marker for multiple indications in cancer, including diagnosis, prognosis, and …

Liquid biopsies come of age: towards implementation of circulating tumour DNA

JCM Wan, C Massie, J Garcia-Corbacho… - Nature Reviews …, 2017 - nature.com
Improvements in genomic and molecular methods are expanding the range of potential
applications for circulating tumour DNA (ctDNA), both in a research setting and as a'liquid …

Oesophageal cancer

EC Smyth, J Lagergren, RC Fitzgerald… - Nature reviews Disease …, 2017 - nature.com
Oesophageal cancer is the sixth most common cause of cancer-related death worldwide
and is therefore a major global health challenge. The two major subtypes of oesophageal …

[HTML][HTML] Cytosponge-trefoil factor 3 versus usual care to identify Barrett's oesophagus in a primary care setting: a multicentre, pragmatic, randomised controlled trial

RC Fitzgerald, M di Pietro, M O'Donovan, R Maroni… - The Lancet, 2020 - thelancet.com
Summary Background Treatment of dysplastic Barrett's oesophagus prevents progression to
adenocarcinoma; however, the optimal diagnostic strategy for Barrett's oesophagus is …

Endoscopic management of early adenocarcinoma and squamous cell carcinoma of the esophagus: screening, diagnosis, and therapy

M di Pietro, MI Canto, RC Fitzgerald - Gastroenterology, 2018 - Elsevier
Because the esophagus is easily accessible with endoscopy, early diagnosis and curative
treatment of esophageal cancer is possible. However, diagnosis is often delayed because …

[HTML][HTML] Use of a cytosponge biomarker panel to prioritise endoscopic barrett's oesophagus surveillance: a cross-sectional study followed by a real-world prospective …

ND Pilonis, S Killcoyne, WK Tan, M O'Donovan… - The Lancet …, 2022 - thelancet.com
Background Endoscopic surveillance is recommended for patients with Barrett's
oesophagus because, although the progression risk is low, endoscopic intervention is highly …

Future cancer research priorities in the USA: a Lancet Oncology Commission

EM Jaffee, C Van Dang, DB Agus… - The Lancet …, 2017 - thelancet.com
We are in the midst of a technological revolution that is providing new insights into human
biology and cancer. In this era of big data, we are amassing large amounts of information …

Precancer atlas to drive precision prevention trials

A Spira, MB Yurgelun, L Alexandrov, A Rao, R Bejar… - Cancer research, 2017 - AACR
Cancer development is a complex process driven by inherited and acquired molecular and
cellular alterations. Prevention is the holy grail of cancer elimination, but making this a reality …

Oesophageal cancer: risks, prevention, and diagnosis

SG Thrumurthy, MA Chaudry, SSD Thrumurthy… - Bmj, 2019 - bmj.com
Oesophageal cancer is currently the sixth commonest source of cancer-associated death
across the world: 572 034 new cases and 508 585 mortalities were reported in 2018. 1 …