Fluorine-18 radiochemistry, labeling strategies and synthetic routes
O Jacobson, DO Kiesewetter, X Chen - Bioconjugate chemistry, 2015 - ACS Publications
Fluorine-18 is the most frequently used radioisotope in positron emission tomography (PET)
radiopharmaceuticals in both clinical and preclinical research. Its physical and nuclear …
radiopharmaceuticals in both clinical and preclinical research. Its physical and nuclear …
18F Labeling of Arenes
M Tredwell, V Gouverneur - Angewandte Chemie International …, 2012 - Wiley Online Library
Molecular imaging has witnessed an upsurge in growth, with positron emission tomography
leading the way. This trend has encouraged numerous synthetic chemists to enter the field …
leading the way. This trend has encouraged numerous synthetic chemists to enter the field …
Closing the gap between 19F and 18F chemistry
Positron emission tomography (PET) has become an invaluable tool for drug discovery and
diagnosis. The positron-emitting radionuclide fluorine-18 is frequently used in PET …
diagnosis. The positron-emitting radionuclide fluorine-18 is frequently used in PET …
Improved 18F Labeling of Peptides with a Fluoride-Aluminum-Chelate Complex
WJ McBride, CA D'Souza, RM Sharkey… - Bioconjugate …, 2010 - ACS Publications
We reported previously the feasibility to radiolabel peptides with fluorine-18 (18F) using a
rapid one-pot method that first mixes 18F− with Al3+ and then binds the (Al18F) 2+ complex …
rapid one-pot method that first mixes 18F− with Al3+ and then binds the (Al18F) 2+ complex …
[图书][B] Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics, and Agrochemicals: Progress in Fluorine Science Series
G Haufe, F Leroux - 2018 - books.google.com
Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics and Agrochemicals,
volume four in Alain Tressaud's Progress in Fluorine Science series, presents a critical …
volume four in Alain Tressaud's Progress in Fluorine Science series, presents a critical …
High-Yielding Aqueous 18F-Labeling of Peptides via Al18F Chelation
CA D'Souza, WJ McBride, RM Sharkey… - Bioconjugate …, 2011 - ACS Publications
The coordination chemistry of a new pentadentate bifunctional chelator (BFC), NODA-MPAA
1, containing the 1, 4, 7-triazacyclononane-1, 4-diacetate (NODA) motif with a …
1, containing the 1, 4, 7-triazacyclononane-1, 4-diacetate (NODA) motif with a …
Strain‐Promoted Copper‐Free “Click” Chemistry for 18F Radiolabeling of Bombesin
LS Campbell‐Verduyn, L Mirfeizi… - Angewandte Chemie …, 2011 - Wiley Online Library
Bombesin is a 14 amino acid (Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-
NH2) neuropeptide, which binds with high affinity to the gastrin-releasing peptide receptor …
NH2) neuropeptide, which binds with high affinity to the gastrin-releasing peptide receptor …
18F‐Labeling of Sensitive Biomolecules for Positron Emission Tomography
HS Krishnan, L Ma, N Vasdev… - Chemistry–A European …, 2017 - Wiley Online Library
Positron emission tomography (PET) imaging study of fluorine‐18 labeled biomolecules is
an emerging and rapidly growing area for preclinical and clinical research. The present …
an emerging and rapidly growing area for preclinical and clinical research. The present …
Site‐Selective, Late‐Stage C−H 18F‐Fluorination on Unprotected Peptides for Positron Emission Tomography Imaging
Z Yuan, MB Nodwell, H Yang, N Malik… - Angewandte Chemie …, 2018 - Wiley Online Library
Peptides are often ideal ligands for diagnostic molecular imaging due to their ease of
synthesis and tuneable targeting properties. However, labelling unmodified peptides with …
synthesis and tuneable targeting properties. However, labelling unmodified peptides with …
Neither azeotropic drying, nor base nor other additives: a minimalist approach to 18 F-labeling
A novel, efficient, time-saving and reliable radiolabeling procedure via nucleophilic
substitution with [18F] fluoride is described. Different radiolabeled aliphatic and aromatic …
substitution with [18F] fluoride is described. Different radiolabeled aliphatic and aromatic …