Thiazolidinedione (TZD) is one of the privileged heterocyclic rings and has shown many
biological applications in medicinal chemistry and drug discovery. This review covers the …

Glioblastoma multiforme (GBM) is the deadliest brain tumor with a poor prognosis and
limited therapeutic options. Temozolomide (TMZ) is the first-line chemotherapeutic agent …

Background The inherent poor druggability of numerous active pharmaceutical ingredients
(APIs) necessitate the modification of their physicochemical and biopharmaceutical …

The escalating incidence of obesity, diabetes, and insulin resistance has become a
significant global health concern. In this study, we have developed a self-nanoemulsifying …

Aggregation-induced emissive materials are gaining particular attention in the last decades
due to their wide application in different fields, from optical devices to biomedicine. In this …

Diabetic nephropathy (DN) is a progressive kidney disorder that develops as a complication
of diabetes due to long-term exposure to elevated blood glucose levels (BGLs). In this case …

Photodynamic therapy (PDT) is an innovative cancer treatment that utilizes light. When light
irradiates, purpurin-18-N-propylimide methyl ester (P18 N PI ME) generates reactive oxygen …

Neurotensin (NT), a bioactive tridecapeptide aids in diabetic wound healing by modulating
inflammation and angiogenesis. However, its rapid degradation in peptidase‐rich wound …

The 2021 statistics from the International Diabetes Federation reveals that approximately
537 million adults between the ages of 20 and 79 are currently coping with diabetes …

Fatty acid-derivative prodrugs have been utilized extensively to improve the
physicochemical, biopharmaceutical and pharmacokinetic properties of active …