Multistep automated pharmaceutical syntheses have been a long-term industrial goal.
Automation not only enables the rapid and highly efficient preparation of organic …

Contemporary materials discovery requires intricate sequences of synthesis, formulation,
and characterization that often span multiple locations with specialized expertise or …

Building automated platforms in chemical processes is a shared goal by many researchers.
Herein, we provide essential insights into the decision-making process for choosing …

Automation and digitalization solutions in the field of small molecule synthesis face new
challenges for chemical reaction analysis, especially in the field of high-performance liquid …

Kinetic investigations can provide critical mechanistic information for the optimization of the
reaction parameters and reaction development. Modern kinetic analyses such as RPKA and …

The amount of chemical synthesis literature is growing quickly; however, it takes a long time
to share and evaluate new processes among laboratories. Here we present an approach …

Monitoring the reaction progress of biphasic reaction mixtures has long presented a
significant challenge to modern analytical techniques. While a multitude of widely utilized …

The recently reported crystallization-induced diastereomer transformation (CIDT) of a
precursor to navoximod was investigated using online HPLC via a modified EasySampler …

Atomically precise gold nanoclusters (AuNCs) are interesting nanomaterials with potential
applications in catalysis, bioimaging and optoelectronics. Their compositions and properties …

Automated chemistry platforms have been widely explored, but many focus on fixed tasks for
chemical synthesis or analysis. However, a typical synthetic chemistry workflow utilizes both …