Nongenomic actions of steroid hormones

R Lösel, M Wehling - Nature reviews Molecular cell biology, 2003 - nature.com
Steroid hormones modulate many physiological processes. The effects of steroids that are
mediated by the modulation of gene expression are known to occur with a time lag of hours …

Thyroid hormones as modulators of immune activities at the cellular level

P De Vito, S Incerpi, JZ Pedersen, P Luly, FB Davis… - Thyroid, 2011 - liebertpub.com
Background: Increasing evidence suggests that thyroid hormones, L-thyroxine (T4) and 3,
3′, 5-triiodo-L-thyronine (T3), are modulators of the immune response. In monocytes …

Integrin αVβ3 Contains a Cell Surface Receptor Site for Thyroid Hormone that Is Linked to Activation of Mitogen-Activated Protein Kinase and Induction of …

JJ Bergh, HY Lin, L Lansing, SN Mohamed… - …, 2005 - academic.oup.com
Integrin αVβ3 is a heterodimeric plasma membrane protein whose several extracellular
matrix protein ligands contain an RGD recognition sequence. This study identifies integrin …

Nongenomic steroid action: controversies, questions, and answers

RM Losel, E Falkenstein, M Feuring… - Physiological …, 2003 - journals.physiology.org
Lösel, Ralf M., Elisabeth Falkenstein, Martin Feuring, Armin Schultz, Hanns-Christian
Tillmann, Karin Rossol-Haseroth, and Martin Wehling. Nongenomic Steroid Action …

[HTML][HTML] Mutations in potassium channel Kir2. 6 cause susceptibility to thyrotoxic hypokalemic periodic paralysis

DP Ryan, MRD da Silva, TW Soong, B Fontaine… - Cell, 2010 - cell.com
Thyrotoxic hypokalemic periodic paralysis (TPP) is characterized by acute attacks of
weakness, hypokalemia, and thyrotoxicosis of various etiologies. These transient attacks …

Mechanisms of thyroid hormone receptor-specific nuclear and extra nuclear actions

JHD Bassett, CB Harvey, GR Williams - Molecular and cellular …, 2003 - Elsevier
Triiodothyronine (T3) classically regulates gene expression by binding to high-affinity thyroid
hormone receptors (TR) that recognize specific response elements in the promoters of T3 …

Genomic and non-genomic mechanisms of action of thyroid hormones and their catabolite 3, 5-diiodo-l-thyronine in mammals

M Giammanco, CM Di Liegro, G Schiera… - International Journal of …, 2020 - mdpi.com
Since the realization that the cellular homologs of a gene found in the retrovirus that
contributes to erythroblastosis in birds (v-erbA), ie the proto-oncogene c-erbA encodes the …

Action of thyroid hormones, T3 and T2, on hepatic fatty acids: differences in metabolic effects and molecular mechanisms

F Damiano, A Rochira, A Gnoni, L Siculella - International journal of …, 2017 - mdpi.com
The thyroid hormones (THs) 3, 3′, 5, 5′-tetraiodo-l-thyronine (T4) and 3, 5, 3′-triiodo-l-
thyronine (T3) influence many metabolic pathways. The major physiological function of THs …

Thyroid hormone regulation and insulin resistance: insights from animals naturally adapted to fasting

B Martinez, RM Ortiz - Physiology, 2017 - journals.physiology.org
The contribution of thyroidal status in insulin signaling and glucose homeostasis has been
implicated as a potential pathophysiological factor in humans, but the specific mechanisms …

Thyroid hormone controls breast cancer cell movement via integrin αV/β3/SRC/FAK/PI3-kinases

MI Flamini, ID Uzair, GE Pennacchio, FJ Neira… - Hormones and …, 2017 - Springer
Thyroid hormones (TH) play a fundamental role in diverse processes, including cellular
movement. Cell migration requires the integration of events that induce changes in cell …