Inflammatory response mechanisms of the dentine–pulp complex and the periapical tissues

KM Galler, M Weber, Y Korkmaz, M Widbiller… - International journal of …, 2021 - mdpi.com
The macroscopic and microscopic anatomy of the oral cavity is complex and unique in the
human body. Soft-tissue structures are in close interaction with mineralized bone, but also …

Dental pulp defence and repair mechanisms in dental caries

JC Farges, B Alliot-Licht, E Renard… - Mediators of …, 2015 - Wiley Online Library
Dental caries is a chronic infectious disease resulting from the penetration of oral bacteria
into the enamel and dentin. Microorganisms subsequently trigger inflammatory responses in …

Inflammation and regeneration in the dentin-pulp complex: a double-edged sword

PR Cooper, MJ Holder, AJ Smith - Journal of endodontics, 2014 - Elsevier
Dental tissue infection and disease result in acute and chronic activation of the innate
immune response, which is mediated by molecular and cellular signaling. Different cell …

Inflammation–regeneration interplay in the dentine–pulp complex

PR Cooper, Y Takahashi, LW Graham, S Simon… - Journal of dentistry, 2010 - Elsevier
OBJECTIVES: Dental tissue disease and trauma provides an excellent model for the
interaction between tissue defence and regenerative processes and has application to many …

Pulp inflammation diagnosis from clinical to inflammatory mediators: a systematic review

M Zanini, E Meyer, S Simon - Journal of endodontics, 2017 - Elsevier
Introduction Similar to other tissues, the dental pulp mounts an inflammatory reaction as a
way to eliminate pathogens and stimulate repair. Pulp inflammation is prerequisite for dentin …

Exploiting the bioactive properties of the dentin-pulp complex in regenerative endodontics

AJ Smith, HF Duncan, A Diogenes, S Simon… - Journal of …, 2016 - Elsevier
Introduction The development of regenerative endodontic therapies offers exciting
opportunities for future improvements in treatment outcomes. Methods Advances in our …

Current state and challenges of the global outcomes of dental caries research in the meta-omics era

DG Moussa, P Ahmad, TA Mansour… - Frontiers in Cellular and …, 2022 - frontiersin.org
Despite significant healthcare advances in the 21st century, the exact etiology of dental
caries remains unsolved. The past two decades have witnessed a tremendous growth in our …

Inflammatory and immunological aspects of dental pulp repair

M Goldberg, JC Farges, S Lacerda-Pinheiro… - Pharmacological …, 2008 - Elsevier
The repair of dental pulp by direct capping with calcium hydroxide or by implantation of
bioactive extracellular matrix (ECM) molecules implies a cascade of four steps: a moderate …

Innate immune responses of the dental pulp to caries

CL Hahn, FR Liewehr - Journal of endodontics, 2007 - Elsevier
Various cells and inflammatory mediators are involved in the initial pulpal responses to
caries. This review focuses on the cellular, neuronal, and vascular components of pulpal …

Molecular detection, quantification, and isolation of Streptococcus gallolyticus bacteria colonizing colorectal tumors: inflammation-driven potential of carcinogenesis …

AS Abdulamir, RR Hafidh, FA Bakar - Molecular cancer, 2010 - Springer
Background Colorectal cancer (CRC) has long been associated with bacteremia and/or
endocarditis by Streptococcus gallolyticus member bacteria (SGMB) but the direct …