Unveiling the proteome-wide autoreactome enables enhanced evaluation of emerging CAR T cell therapies in autoimmunity

A Bodansky, JL David, A Rallistan, M Kalaycioglu… - The Journal of clinical …, 2024 - jci.org
Given the global surge in autoimmune diseases, it is critical to evaluate emerging
therapeutic interventions. Despite numerous new targeted immunomodulatory therapies …

Current treatment approach, emerging therapies and new horizons in systemic lupus erythematosus

P Athanassiou, L Athanassiou - Life, 2023 - mdpi.com
Systemic lupus erythematosus (SLE), the prototype of systemic autoimmune diseases is
characterized by extreme heterogeneity with a variable clinical course. Renal involvement …

Roles of probiotics, prebiotics, and postbiotics in B-cell-mediated immune regulation

R Wang, FY Yifei, RY Weiru, SY Sun, YM Lei, YX Li… - The Journal of …, 2025 - Elsevier
Probiotics, prebiotics, and postbiotics can significantly influence B-cell-related diseases
through their immunomodulatory effects. They enhance the immune system's function …

[HTML][HTML] Современная концепция аутоиммунитета в ревматологии

ЕЛ Насонов - Научно-практическая ревматология, 2023 - cyberleninka.ru
В спектре механизмов хронического воспаления центральное место занимают два
фундаментальных патологических процесса-аутоиммунитет и аутовоспаление …

[PDF][PDF] Regenerating damaged joints: the promise of tissue engineering and nanomedicine in lupus arthritis

TA Addissouky, IET El Sayed… - J Clinical Orthopaedics and …, 2024 - researchgate.net
Background: Lupus osteoarthritis is a disabling complication of systemic lupus
erythematosus (SLE) caused by persistent inflammation and biomechanical factors. The …

[HTML][HTML] Cryptogenic Organizing Pneumonia Is Associated With Increased Mortality Risk in Hospitalizations for Systemic Lupus Erythematosus (SLE): A National …

FE Uwumiro, A Emmanuel, C Offiah, N Umeani… - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
Background This study analyzed the incidence, characteristics, and mortality risk associated
with cryptogenic organizing pneumonia (COP) among hospitalizations for systemic lupus …

Effectiveness and safety of B cell-targeting biologics in the treatment of lupus nephritis: a systematic review and network meta‑analysis

X Zhao, SQ Yang, M Li, YG Wang - Renal Failure, 2024 - Taylor & Francis
Objectives To evaluate the effectiveness and safety of different B cell-targeting biological
agents combining with standard of care in patients with lupus nephritis (LN). Methods …

The Immunobiological agents for treatment of Antiglomerular Basement membrane disease

M Yamashita, M Takayasu, H Maruyama, K Hirayama - Medicina, 2023 - mdpi.com
Combination therapy with glucocorticoids, cyclophosphamide, and plasmapheresis is
recommended as the standard treatment for anti-glomerular basement membrane (anti …

Comparative efficacy and safety of different recommended doses of telitacicept in patients with systemic lupus erythematosus in China: a systematic review and meta …

S Gao, C Yang, B Huang, L Yang, L Lu… - Frontiers in …, 2025 - frontiersin.org
Background Telitacicept, a new biological agent, was approved in China for treating
systemic lupus erythematosus (SLE) in 2021. Its optimal dosing for treating SLE remains …

[HTML][HTML] Unveiling the autoreactome: Proteome-wide immunological fingerprints reveal the promise of plasma cell depleting therapy

A Bodansky, JL David, A Rallistan, M Kalaycioglu… - MedRxiv, 2023 - ncbi.nlm.nih.gov
The prevalence and burden of autoimmune and autoantibody mediated disease is
increasing worldwide, yet most disease etiologies remain unclear. Despite numerous new …