Molecular targets of vitexin and isovitexin in cancer therapy: a critical review

K Ganesan, B Xu - Annals of the New York Academy of …, 2017 - Wiley Online Library
Cancer is a primary public health problem and the second leading cause of death
worldwide. It causes life‐threatening malignancies and results in high financial costs for both …

Genus Gentiana: A review on phytochemistry, pharmacology and molecular mechanism

M Jiang, BW Cui, YL Wu, JX Nan, LH Lian - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance As the largest genus of Gentianaceae family, the Gentiana
genus harbors over 400 species, widely distributed in the alpine areas of temperate regions …

Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway

MH Soflaee, R Kesavan, U Sahu, A Tasdogan… - Nature …, 2022 - nature.com
Purine nucleotides are necessary for various biological processes related to cell
proliferation. Despite their importance in DNA and RNA synthesis, cellular signaling, and …

The healing bitterness of Gentiana lutea L., phytochemistry and biological activities: A systematic review

M Ponticelli, L Lela, M Moles, C Mangieri, D Bisaccia… - Phytochemistry, 2023 - Elsevier
Over many years, natural products have been a source of healing agents and have
exhibited beneficial uses for treating human diseases. The Gentiana genus is the biggest …

Traditional use of medicinal plants in South-Eastern Serbia (Pčinja District): Ethnopharmacological investigation on the current status and comparison with half a …

J Živković, M Ilić, K Šavikin, G Zdunić, A Ilić… - Frontiers in …, 2020 - frontiersin.org
Balkan Peninsula is one of the most important biodiversity centers in Europe. Despite that,
the usage of plant species in the traditional medicine of some Balkan regions remained …

Anti-Inflammatory Effects of Phytochemical Components of Clinacanthus nutans

WY Ong, DR Herr, GY Sun, TN Lin - Molecules, 2022 - mdpi.com
Recent studies on the ethnomedicinal use of Clinacanthus nutans suggest promising anti-
inflammatory, anti-tumorigenic, and antiviral properties for this plant. Extraction of the leaves …

Loganic Acid, an Iridoid Glycoside Extracted from Cornus mas L. Fruits, Reduces of Carbonyl/Oxidative Stress Biomarkers in Plasma and Restores Antioxidant …

O Dzydzan, I Brodyak, A Sokół-Łętowska… - Life, 2020 - mdpi.com
The various complications related to diabetes are due to the alteration in plasma
components and functional activity of blood cells, hence the search for preventive remedies …

Receptor tyrosine kinase: still an interesting target to inhibit the proliferation of vascular smooth muscle cells

Y Xiong, Y Wang, T Yang, Y Luo, S Xu, L Li - American Journal of …, 2023 - Springer
Vascular smooth muscle cells (VSMCs) proliferation is a critical event that contributes to the
pathogenesis of vascular remodeling such as hypertension, restenosis, and pulmonary …

Effects of phytochemicals on cellular signaling: reviewing their recent usage approaches

DC Pham, MA Shibu, B Mahalakshmi… - Critical reviews in …, 2020 - Taylor & Francis
Most of the previous studies in last three decades report evidence of interactions between
the different phytochemicals and the proteins involved in signal transduction pathways using …

Analytical Methods of Phytochemicals from the Genus Gentiana

Y Xu, Y Li, K G. Maffucci, L Huang, R Zeng - Molecules, 2017 - mdpi.com
The genus Gentiana comprises approximately 400 species. Many species have a wide
range of pharmacological activities and have been used therapeutically for thousands of …