Integrated immunologic monitoring in solid organ transplantation: the road toward torque Teno virus-guided immunosuppression

P Jaksch, I Görzer, E Puchhammer-Stöckl… - Transplantation, 2022 - journals.lww.com
Potent immunosuppressive drugs have been introduced into clinical care for solid organ
transplant recipients. It is now time to guide these drugs on an individual level to optimize …

Microbial transmission in the social microbiome and host health and disease

A Sarkar, CJA McInroy, S Harty, A Raulo, NGO Ibata… - Cell, 2024 - cell.com
Although social interactions are known to drive pathogen transmission, the contributions of
socially transmissible host-associated mutualists and commensals to host health and …

The enigmatic roles of Anelloviridae and Redondoviridae in humans

LJ Taylor, EL Keeler, FD Bushman… - Current Opinion in …, 2022 - Elsevier
Anelloviridae and Redondoviridae are virus families with small, circular, single-stranded
DNA genomes that are common components of the human virome. Despite their small …

Diversity and long-term dynamics of human blood anelloviruses

J Kaczorowska, M Deijs, M Klein, M Bakker… - Journal of …, 2022 - Am Soc Microbiol
Anelloviruses (AVs) are commensal members of the human blood virome. Even though it
was estimated that over 90% of the human population carries AVs, the dynamics of the AV …

Spatial scale influences the distribution of viral diversity in the eukaryotic virome of the mosquito Culex pipiens

P Gil, A Exbrayat, E Loire, I Rakotoarivony… - Virus …, 2023 - academic.oup.com
Our knowledge of the diversity of eukaryotic viruses has recently undergone a massive
expansion. This diversity could influence host physiology through yet unknown phenomena …

Evolution of anelloviruses from a circovirus-like ancestor through gradual augmentation of the jelly-roll capsid protein

A Butkovic, S Kraberger, Z Smeele, DP Martin… - Virus …, 2023 - academic.oup.com
Anelloviruses are highly prevalent in diverse mammals, including humans, but so far have
not been linked to any disease and are considered to be part of the 'healthy virome'. These …

Human Anelloviruses: influence of demographic factors, recombination, and worldwide diversity

M Cebriá-Mendoza, B Beamud… - Microbiology …, 2023 - Am Soc Microbiol
Anelloviruses represent the major and most diverse component of the healthy human
virome, referred to as the anellome. In this study, we determined the anellome of 50 blood …

A unified model of age-related cardiovascular disease

M Fossel, J Bean, N Khera, MG Kolonin - Biology, 2022 - mdpi.com
Simple Summary Age-related cardiovascular disease is the foremost cause of death
globally. Despite medical advances, we have been unable to stop or reverse the underlying …

Respiratory virome profiles reflect antiviral immune responses

J Rovira Rubió, S Megremis, M Pasioti… - Allergy, 2023 - Wiley Online Library
Background From early life, respiratory viruses are implicated in the development,
exacerbation and persistence of respiratory conditions such as asthma. Complex dynamics …

Comprehensive profiling of antibody responses to the human anellome using programmable phage display

T Venkataraman, H Swaminathan, CA Arze… - Cell Reports, 2022 - cell.com
Anelloviruses represent a major constituent of the commensal human virome; however, little
is known about their immunobiology. Here, we present" AnelloScan," a T7 phage library …