Innate immunity in bacteria, plants, and animals requires the specialized subset of Toll/interleukin-1/resistance gene (TIR) domain proteins that are nicotinamide adenine …
The TIR (Toll/interleukin-1 receptor) domain represents a vital structural element shared by proteins with roles in immunity signalling pathways across phyla (from humans and plants to …
Innate immunity in bacteria, plants and animals requires the specialized subset of TIR- domain proteins that are NAD+ hydrolases. Aggregation of these TIR proteins engages their …
SY Tse-Kang, KA Wani, ND Peterson, A Page… - bioRxiv, 2023 - biorxiv.org
Mechanisms of pathogen recognition in barrier tissues, which interface with both commensal and virulent bacteria, are critical for health and not fully understood. Here, we discovered a …
M Paglione, L Restivo, S Zakhia, AL Rosell, M Terenzio… - bioRxiv, 2023 - biorxiv.org
After injury, the severed axon separated from the soma activates programmed axon degeneration, an evolutionarily conserved pathway to initiate its degeneration within a day …
M Paglione, L Restivo, S Zakhia, AL Rosell, M Terenzio… - scholar.archive.org
After injury, the axon separated from the soma activates programmed axon degeneration, an evolutionarily conserved pathway to initiate its degeneration within a day. However, in …