Mouse embryonic stem (ES) cells are pluripotent cells that differentiate into multiple cell
lineages. The commitment of ES cells into the adipocyte lineage is dependent on an early 3 …

Neural proliferation and differentiation control protein-1 (NPDC-1) is a protein expressed
primarily in brain and lung and whose expression can be correlated with the regulation of …

Acute promyelocytic leukemia (APL) is a treatment success story. From a highly deadly
disease, it was turned into a highly curable disease by the introduction of differentiation …

MAPK signaling is required for retinoic acid (RA)-triggered G 0 cell cycle arrest and cell
differentiation, but the mechanism is not well defined. In this study, RA is found to cause …

6-Formylindolo (3, 2-b) carbazole (FICZ) is a photoproduct of tryptophan and an
endogenous high affinity ligand for aryl hydrocarbon receptor (AhR). It was previously …

Background The aryl hydrocarbon receptor (AhR) ligand 6-Formylindolo (3, 2-b) carbazole
(FICZ) has received increasing attention since its identification as an endogenous AhR …

The mechanism of action of retinoic acid (RA) is of broad relevance to cell and
developmental biology, nutrition, and cancer chemotherapy. RA is known to induce …

Retinoic acid‐induced expression of the CD38 ectoenzyme receptor in HL‐60 human
myeloblastic leukemia cells is regulated by RARα and RXR, and enhanced or prevented cell …

Novel functions of signaling molecules have been revealed in studies of cancer stem cells.
Retinoic acid (RA) is an embryonic morphogen and stem cell regulator that controls the …

In binary cell-fate decisions, driving one lineage and suppressing the other are conjoined.
We have previously reported that aryl hydrocarbon receptor (AhR) promotes retinoic acid …