The quest for an effective dengue vaccine has culminated in two approved vaccines and
another that has completed phase 3 clinical trials. However, shortcomings exist in each …

Integration of viral DNA into the host genome is a central event in the replication cycle and
the pathogenesis of retroviruses, including HIV. Although most cells infected with HIV are …

Single-cell technology has a major impact on the field of immunology. It enables the kinetics
and logic of immune signaling and immune cell migration to be elucidated, facilitates …

BACKGROUND Single-cell genomics is an approach to investigate cell heterogeneity and to
identify new molecular features correlated with clinical outcomes. This approach allows …

The ability to rapidly assess and monitor patient immune responses is critical for clinical
diagnostics, vaccine design, and fundamental investigations into the presence or generation …

Globally, it is estimated that one-quarter of the world's population is latently infected with
Mycobacterium tuberculosis (Mtb), also known as latent tuberculosis infection (LTBI) …

The devastating COVID-19 pandemic caused by SARS-CoV-2 and multiple variants or
subvariants remains an ongoing global challenge. SARS-CoV-2-specific T cell responses …

It is generally recognized that dysregulation of the immune system plays a critical role in
many diseases, including autoimmune diseases and cancer. T cells play a crucial role in …

This study sought to elucidate the mechanisms underlying the impact of the interferon
signaling pathway on Ferroptosis in tumor cells and its correlation with CD8+ T cell …

HIV-1 reservoirs are most often studied in peripheral blood (PB), but not all lymphocytes
recirculate, particularly T follicular helper (Tfh) CD4+ T cells, as well as germinal center (GC) …