Delivering a drug to the target site with minimal-to-no off-target cytotoxicity is the major
determinant for the success of disease therapy. While the therapeutic efficacy and …

Here, a spotlight is shown on aqueous microgel particles which exhibit a great potential for
various biomedical applications such as drug delivery, cell imaging, and tissue engineering …

The polymers, chitosan, a polysaccharide, and gelatin, a protein, are crosslinked in different
ratios without the aid of a crosslinking agent. Facile chemical reactions were followed to …

Retinoblastoma (RB) is a pediatric retinal tumor that overexpresses the ganglioside GD2.
Although it is treatable in patients with early diagnosis, patients may lose one or two eyes …

The spinal cord is part of the central nervous system (CNS) and serves to connect the brain
to the peripheral nervous system and peripheral tissues. The cell types that primarily …

The ready-to-use, structure-supporting hydrogel bioink can shorten the time for ink
preparation, ensure cell dispersion, and maintain the preset shape/microstructure without …

Chitosan based microgels have gained great attention because of their chemical stability,
biocompatibility, easy functionalization and potential uses in numerous fields. Production …

Degradable hydrogels to deliver bioactive proteins represent an emerging platform for
promoting tissue repair and vascularization in various applications. However, implanting …

In the present work, hybrid microgels based on chitosan and SiO 2 nanoparticles (NPs) were
synthesized. Both chitosan and the SiO 2 NPs were submitted to chemical modification …

In this study, the paracrine effect between adipose-derived mesenchymal stem cells
(ADSCs) and osteoblasts was investigated in collagen-based three-dimensional (3D) …