Hepatic steatosis is an underlying feature of nonalcoholic fatty liver disease (NAFLD), which
is the most common form of liver disease and is present in up to∼ 70% of individuals who …

Lipoprotein lipase (LPL) is one of the most important factors in systemic lipid partitioning and
metabolism. It mediates intravascular hydrolysis of triglycerides packed in lipoproteins such …

Background Higher-than-normal levels of circulating triglycerides are a risk factor for
ischemic cardiovascular disease. Activation of lipoprotein lipase, an enzyme that is inhibited …

Abstract In mammals, triglyceride (TG), the main form of lipids for storing and providing
energy, is stored in white adipose tissue (WAT) after food intake, while during fasting it is …

Triglyceride-rich lipoproteins deliver fatty acids to tissues for oxidation and for storage.
Release of fatty acids from circulating lipoprotein triglycerides is carried out by lipoprotein …

Triglycerides and cholesterol circulate in the bloodstream as part of various lipoprotein
particles. Three members of the angiopoietin-like (ANGPTL) protein family—ANGPTL3 …

Triglycerides are carried in the bloodstream as the components of very low-density
lipoproteins and chylomicrons. These circulating triglycerides are primarily hydrolyzed in …

Abstract Angiopoietin-like (ANGPTL) 3 and ANGPTL8 are secreted proteins and inhibitors of
LPL-mediated plasma triglyceride (TG) clearance. It is unclear how these two ANGPTL …

The angiopoietin‐like 4 (ANGPTL4) protein belongs to a superfamily of secreted proteins
structurally related to factors modulating angiogenesis known as angiopoietins. At first …

The past decade has seen a rapid development and increasing recognition of ANGPTL4
(angiopoietin-like 4) as a remarkably multifaceted protein that is involved in many metabolic …