Acute respiratory distress syndrome (ARDS) is a severe form of respiratory failure burden by
high hospital mortality. No specific pharmacologic treatment is currently available and its …

Background Several studies have found only a weak to moderate correlation between
oxygenation and lung aeration in response to changes in PEEP. This study aimed to …

Background: Arterial oxygenation is often impaired during one-lung ventilation, due to both
pulmonary shunt and atelectasis. The use of low tidal volume (VT)(5 ml/kg predicted body …

Mechanical ventilation is a very effective therapy, but with many complications. Simulators
are used in many fields, including medicine, to enhance safety issues. In the intensive care …

During one-lung ventilation (OLV), titrating the positive end-expiratory pressure (PEEP) to
target a low driving pressure (∆ P) could reduce postoperative pulmonary complications …

We describe a three-compartment model (shunt and two perfused compartments) to analyse
the relationship between inspired oxygen (FIO 2) and arterial oxygen saturation (S a O 2) in …

Tight control of systemic oxygenation is a key component of mechanical ventilation of
critically ill patients. Yet, closed-loop control remains challenging due to the non-linear …

Background: Postoperative pulmonary complications can increase hospital length of stay,
postoperative morbidity, and mortality. Although many factors can increase the risk of …

The common pulmonary consequence of SARS-CoV-2 infection is pneumonia, but vascular
clot may also contribute to COVID pathogenesis. Imaging and hemodynamic approaches to …

Background Computer simulation models could play a key role in developing novel
therapeutic strategies for patients with chronic obstructive pulmonary disease (COPD) if they …