This article describes methods used to estimate parameters governing long-term survival, or
times to other events, for health economic models. Specifically, the focus is on methods that …

Health economic models rely on data from trials to project the risk of events (eg, death) over
time beyond the span of the available data. Parametric survival analysis methods can be …

Purpose With three available chemotherapy drugs for advanced colorectal cancer (CRC),
response rate (RR) and survival outcomes have improved with associated morbidity …

Purpose: This study aimed to identify a novel biomarker or a target of treatment for colorectal
cancer (CRC). Experimental Design: The expression profiles of cancer cells in 104 patients …

Background We evaluated the prognostic value of the preoperative serum carcinoembryonic
antigen (CEA) level in patients with colorectal cancer (CRC). Patients and Methods The …

Distant metastasis is the major cause of death in colorectal cancer (CRC) patients. To
identify genes influencing the prognosis of patients with CRC, we compared gene …

Purpose Hepatitis B virus (HBV) reactivation is a potentially fatal complication of
chemotherapy that can be largely prevented with antiviral prophylaxis. It remains unclear …

BACKGROUND. Adding trastuzumab to adjuvant chemotherapy provides significant clinical
benefit in patients with human epidermal growth factor receptor 2 (HER2)‐positive breast …

Objectives Survival extrapolation of trial outcomes is required for health economic
evaluation. Generally, all-cause mortality (ACM) is modeled using standard parametric …

Colon cancer is seen with increasing frequency in the Asia-Pacific region, and it is one of the
most important causes of cancer mortality worldwide. This article reviews the available …